6-[5-(Ethoxyamino)-3-hydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-[5-(Ethoxyamino)-3-hydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid
• 英文别名: 6-[5-(ethoxyamino)-3-hydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid
• 化学式: C₁₆H₂₉NO₁₁
• 分子量: 411.4
• InChiKey: RGGUCNJEDZJRAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  176
• 氢给体数：
  6
• 氢受体数：
  12

文献信息

• Amphoteric Materials Based on Crosslinked Hyaluronic Acid, Method of Preparation Thereof, Materials Containing Entrapped Active Agents, Method of Preparation Thereof, and Use of Said Materials
  申请人：CONTIPRO BIOTECH S.R.O.

  公开号：US20140120069A1

  公开（公告）日：2014-05-01

  The present invention describes novel amphoteric materials based on crosslinked hyaluronic acid, according to the general formula (I), and a method of preparation of said materials. Further, the invention relates to the material containing entrapped active agents (e.g. drugs, growth factors etc.) and a method of preparation thereof. Moreover, the present invention relates to the use of said materials for controlled release systems, in tissue engineering, wound dressing or tissue regeneration.

  本发明描述了基于交联透明质酸的新型两性材料，其符合通用式(I)，以及该材料的制备方法。此外，本发明涉及含有包埋活性剂（如药物、生长因子等）的材料及其制备方法。此外，本发明还涉及将所述材料用于控制释放系统、组织工程、伤口敷料或组织再生的用途。
• Nanofibers Containing Photocurable Ester Derivative of Hyaluronic Acid or Its Salt, Photocured Nanofibers, Method of Synthesis Thereof, Preparation Containing Photocured Nanofibers and Use Thereof
  申请人：CONTIPRO BIOTECH S R.O.

  公开号：US20160312385A1

  公开（公告）日：2016-10-27

  The invention relates to nanofibers containing photocurable ester derivatives of hyaluronic acid or its salt, the method of preparation thereof, and the photocured preparation made from the nanofibers by light irradiation and the use thereof