6-[3-(Ethoxyamino)-5-hydroxy-2-methoxy-6-[(prop-2-ynylamino)methyl]oxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-[3-(Ethoxyamino)-5-hydroxy-2-methoxy-6-[(prop-2-ynylamino)methyl]oxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid
• 英文别名: 6-[3-(ethoxyamino)-5-hydroxy-2-methoxy-6-[(prop-2-ynylamino)methyl]oxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid
• 化学式: C₁₉H₃₂N₂O₁₀
• 分子量: 448.5
• InChiKey: UNBCUDZNVAUXMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.8
• 重原子数：
  31
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  168
• 氢给体数：
  6
• 氢受体数：
  12

文献信息

• Amphoteric Materials Based on Crosslinked Hyaluronic Acid, Method of Preparation Thereof, Materials Containing Entrapped Active Agents, Method of Preparation Thereof, and Use of Said Materials
  申请人：CONTIPRO BIOTECH S.R.O.

  公开号：US20140120069A1

  公开（公告）日：2014-05-01

  The present invention describes novel amphoteric materials based on crosslinked hyaluronic acid, according to the general formula (I), and a method of preparation of said materials. Further, the invention relates to the material containing entrapped active agents (e.g. drugs, growth factors etc.) and a method of preparation thereof. Moreover, the present invention relates to the use of said materials for controlled release systems, in tissue engineering, wound dressing or tissue regeneration.

  本发明描述了基于交联透明质酸的新型两性材料，其符合通用式(I)，以及该材料的制备方法。此外，本发明涉及含有包埋活性剂（如药物、生长因子等）的材料及其制备方法。此外，本发明还涉及将所述材料用于控制释放系统、组织工程、伤口敷料或组织再生的用途。