(3S)-5-bromo-3-methylpentan-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3S)-5-bromo-3-methylpentan-2-one
• 化学式: C₆H₁₁BrO
• 分子量: 179.05
• InChiKey: JHVBVETVQZPKDG-YFKPBYRVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Modified Compstatin With Improved Stability And Binding Properties
  申请人：Lambris John D.

  公开号：US20140113874A1

  公开（公告）日：2014-04-24

  Compounds comprising peptides capable of binding C3 protein and inhibiting complement activation are disclosed. These cyclic compounds are modified to improve stability while maintaining substantially equivalent complement activation-inhibitory activity as compared with currently available compounds. The compounds comprise compstatin analogs in which the disulfide bond between C2 and C12 is modified via a thioether bond to form a cystathionine.