1-Methyl-3-propan-2-yloxycyclobutane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Methyl-3-propan-2-yloxycyclobutane
• 英文别名: 1-methyl-3-propan-2-yloxycyclobutane
• 化学式: C₈H₁₆O
• 分子量: 128.21
• InChiKey: LNZRSYFJFFVMTO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
  申请人：Bellenie Benjamin Richard

  公开号：US10004732B2

  公开（公告）日：2018-06-26

  The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.

  本发明提供了抑制 PI 3-kinase gamma 异构体活性的式 (I) 化合物，可用于治疗由 PI 3-kinase gamma 异构体活化介导的疾病。
• AMINO PYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
  申请人：BELLENIE Benjamin Richard

  公开号：US20170037032A1

  公开（公告）日：2017-02-09

  The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
• AMINO PYRAZINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
  申请人：BELLENIE Benjamin Richard

  公开号：US20170042889A1

  公开（公告）日：2017-02-16

  The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
• [EN] TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF<br/>[FR] COMPOSÉ TRIAZOLE-ISOXAZOLE ET UTILISATION MÉDICALE DE CELUI-CI
  申请人：JAPAN TOBACCO INC

  公开号：WO2014065413A1

  公开（公告）日：2014-05-01

  　下記一般式［Ｉ］で表される化合物又はその医薬上許容される塩。（式中、各記号は明細書に記載の通りである。）