N-((5-acrylamido-3,4,6-trihydroxytetrahydro-2H-pyran-2-yl)methyl)acrylamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-((5-acrylamido-3,4,6-trihydroxytetrahydro-2H-pyran-2-yl)methyl)acrylamide
• 英文别名: N-[[3,4,6-trihydroxy-5-(prop-2-enoylamino)oxan-2-yl]methyl]prop-2-enamide
• 化学式: C₁₂H₁₈N₂O₆
• 分子量: 286.285
• InChiKey: CCZSVQWDPOCCHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  128
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• [EN] ACRYLAMIDE DERIVATIVES<br/>[FR] DÉRIVÉS D'ACRYLAMIDE
  申请人：EMPIRE TECHNOLOGY DEV LLC

  公开号：WO2014070192A1

  公开（公告）日：2014-05-08

  Embodiments presented herein relate to acrylamide derivatives and uses thereof. Examples of such derivatives include acrylamide pyranose and other acrylamides that have other carbohydrate or 5 or 6 membered rings attached thereto. The compositions can be used for a variety of purposes, e.g., cosmetics, construction, scaffold materials, hydrogels, food additives, baby diapers, tubing sieves, etc.

  本文所述实施例涉及丙烯酰胺衍生物及其用途。此类衍生物的例子包括丙烯酰胺吡喃糖和其他连接有其他碳水化合物或5或6个成员环的丙烯酰胺。这些组合物可用于各种目的，例如化妆品、建筑、支架材料、水凝胶、食品添加剂、婴儿尿布、管道筛等。
• HIGH PERFORMANCE ACRYLAMIDE ADHESIVES
  申请人：Empire Technology Development LLC

  公开号：US20140155563A1

  公开（公告）日：2014-06-05

  Disclosed are derivatives of (tetrahydropyranyl)methyl acrylamide and polymers derived therefrom, as well as methods of making such compounds and polymers. Adhesives, coatings, and plastics which include such polymers are also described.

  本发明涉及（四氢吡喃基）甲基丙烯酰胺的衍生物及其衍生的聚合物，以及制备这些化合物和聚合物的方法。还描述了包括这种聚合物的粘合剂、涂料和塑料。
• CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY
  申请人：Cheng Jianjun

  公开号：US20130039880A1

  公开（公告）日：2013-02-14

  The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.

  本发明涉及一种新型治疗环糊精含聚合物化合物的组合物，其设计为小分子治疗剂的载体，并且涉及其制药组合物。这些含有环糊精的聚合物可以提高药物的稳定性和溶解度，并在体内使用时减少小分子治疗剂的毒性。此外，通过从各种连接基团和靶向配体中选择，这些聚合物提供了治疗剂的控制释放方法。本发明还涉及使用上述治疗组合物治疗受试者的方法。本发明还涉及制药业务的方法，包括制造、许可或分发包含或涉及上述聚合物化合物的试剂盒。
• ACRYLAMIDE HYDROGELS FOR TISSUE ENGINEERING
  申请人：Carlson William B.

  公开号：US20140178344A1

  公开（公告）日：2014-06-26

  Disclosed are acrylamide hydrogels prepared from derivatives of (tetrahydropyranyl)methyl- and (tetrahydrofuranyl)methyl-acrylamide, methods of making the same, and methods of wound healing or tissue generation with acrylamide hydrogels.
• ACRYLAMIDE DERIVATIVES
  申请人：EMPIRE TECHNOLOGY DEVELOPMENT LLC

  公开号：US20150272854A1

  公开（公告）日：2015-10-01

  Embodiments presented herein relate to acrylamide derivatives and uses thereof. Examples of such derivatives include acrylamide pyranose and other acrylamides that have other carbohydrate or 5 or 6 membered rings attached thereto. The compositions can be used for a variety of purposes, e.g., cosmetics, construction, scaffold materials, hydrogels, food additives, baby diapers, tubing sieves, etc.