2-(1-Methylcyclohexa-2,4-dien-1-yl)acetaldehyde

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(1-Methylcyclohexa-2,4-dien-1-yl)acetaldehyde
• 英文别名: 2-(1-methylcyclohexa-2,4-dien-1-yl)acetaldehyde
• 化学式: C₉H₁₂O
• 分子量: 136.19
• InChiKey: ZBXZJWPLSZFQEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• USE OF BACTERIAL BETA-LACTAMASE FOR IN VITRO DIAGNOSTICS AND IN VIVO IMAGING, DIAGNOSTICS AND THERAPEUTICS
  申请人：Cirillo Jeffrey D.

  公开号：US20140127712A1

  公开（公告）日：2014-05-08

  Provided herein are assays and in vitro methods to determine susceptibility to a drug effective against a pathogenic bacteria, for example, a pathogenic Mycobacteria, that has a beta-lactamase activity. An excitation wavelength is delivered to a biological sample obtained from a subject having an infection from the pathogenic bacteria in the presence of a beta-lactamase substrate. The intensity of a signal, such as a fluorescent, luminescent or colorimetric signal, at an emission wavelength of a product of the beta-lactamase on the subject is correlated to drug susceptibility. Also provided is an assay system for monitoring drug susceptibility of a pathogenic bacteria comprising color-producing substrates for a beta-lactamase of the pathogenic bacteria, an assay device for visibly detecting a product of the beta-lactamase on the substrate thereof and a reader configured to quantify the visibly detected product.
• US9441261B2
  申请人：——

  公开号：US9441261B2

  公开（公告）日：2016-09-13