2-Azidoglucose

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Azidoglucose
• 英文别名: (2R,3S,4R,5R)-2-azido-2,3,4,5,6-pentahydroxyhexanal
• 化学式: C6H11N3O6
• 分子量: 221.17
• InChiKey: KYYLBTDGVAUNBT-ZXXMMSQZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  133
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• Compounds that bind to the interferon-gamma, preparation method thereof and medicaments containing same
  申请人：Bonnaffe David

  公开号：US20060166927A1

  公开（公告）日：2006-07-27

  Compound capable of binding to gamma-interferon (γ-IFN), chosen from the molecules corresponding to formula (I) below: in which X is a divalent spacer group that is sufficiently long to allow the two oligosaccharide fragments A and B to each bind to one of the peptide sequences 125 to 143 of the C-terminal ends of a γ-interferon (γ-IFN) homodimer, n represents an integer from 0 to 10, and for example equal to 0, 1, 2, 3, 4 or 5, and each R independently represents a hydrogen atom, an SO 3 − group or a phosphate group, on the condition that no SO 3 − group is in the 3-position of the glucosamine units of compound (I). The invention also relates to the process for preparing these compounds, to the complexes formed by these compounds and gamma-interferon, and to the medicaments comprising these compounds or complexes.

  能够与干扰素-γ（γ-IFN）结合的化合物，选自符合以下公式（I）的分子：其中X是一个二价间隔基团，足够长以允许两个寡糖片段A和B各自结合到一个γ-干扰素（γ-IFN）同源二聚体的C端末端的肽序列125至143，n代表从0到10的整数，例如等于0、1、2、3、4或5，并且每个R独立代表一个氢原子、一个SO3−基团或一个磷酸基团，条件是在化合物（I）的葡萄糖胺单元的3位上没有SO3−基团。本发明还涉及制备这些化合物的方法，这些化合物与干扰素-γ形成的复合物，以及包含这些化合物或复合物的药物。
• PROCESS FOR THE SYNTHESIS OF L-FUCOSYL DI- OR OLIGO-SACCHARIDES AND NOVEL 2,3,4 TRIBENZYL-FUCOSYL DERIVATIVES INTERMEDIATES THEREOF
  申请人：Salsini Liana

  公开号：US20110245488A1

  公开（公告）日：2011-10-06

  The present invention relates to a process for the synthesis of L-fucosyl di- or oligosaccharides and their novel 2,3,4-tri-O-benzyl-fucosyl synthetic intermediates derivatives of easy crystallization. In particular the present invention relates to a process applicable to industrial scale for the synthesis of 2′O-fucosyl lactose.

  本发明涉及一种合成L-岩藻糖二糖或寡糖的过程，以及易于结晶的新型2,3,4-三-O-苄基-岩藻糖合成中间体衍生物。特别是，本发明涉及一种适用于工业规模的合成2'O-岩藻糖乳糖的过程。
• Polysaccharides and methods and intermediates useful for their preparation
  申请人：Linhardt J. Robert

  公开号：US20050010044A1

  公开（公告）日：2005-01-13

  The invention provides sulfo-protected polysaccharides and methods for preparing sulfo-protected polysaccharides, as well as intermediate compounds useful in such methods.

  本发明提供了磺酸保护的多糖和制备磺酸保护的多糖的方法，以及在这些方法中有用的中间化合物。
• CROSS-LINKING AND STABILIZATION OF ORGANIC METAL COMPLEXES IN NETWORKS
  申请人：Baumann Thomas

  公开号：US20140142258A1

  公开（公告）日：2014-05-22

  The invention relates to the preparation of an organic transition metal complex cross-linked into a multi-dimensional network, comprising the performance of a first reaction, which comprises a first reactant in the form of an organic metal complex and a second reactant for the formation of a multi-dimensional network, where the organic metal complex is cross-linked to form the multi-dimensional-network during the reaction.

  本发明涉及一种制备有机过渡金属配合物交联成多维网络的方法，包括进行第一反应，该反应包括以有机金属配合物形式的第一反应物和用于形成多维网络的第二反应物，其中在反应过程中，有机金属配合物被交联形成多维网络。
• COMPOSES SE LIANT A L INTERFERON-GAMMA, LEUR PROCEDE DE PREPARATION, ET MEDICAMENTS LES CONTENANT
  申请人：COMMISSARIAT A L'ENERGIE ATOMIQUE

  公开号：EP1521779A1

  公开（公告）日：2005-04-13