hexadecane-2,3-dione | 22141-28-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: hexadecane-2,3-dione
• 英文别名: Hexadecanedione
• CAS: 22141-28-2
• 化学式: C₁₆H₃₀O₂
• 分子量: 254.413
• InChiKey: MASKIKMXGSRZHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  18
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-十二烷基丙二酸 生成 hexadecane-2,3-dione
  参考文献：
  名称：

  长链酰基辅酶和邻二酮

  摘要：

  研究了制备长链邻二酮的几种方法。酰基转移酶缩合，然后进行氧化，提供了一种制备对称化合物的极佳途径，但对于不对称二酮而言并不令人满意。后者由（i）由二烷基乙炔经半氢化，羟基化和用N-溴代琥珀酰亚胺水溶液氧化而制得；（ii）由α-乙酰氧基酰氯和双四氢吡喃基或二苄基烷基丙二酸酯的钠衍生物衍生，然后除去保护基并脱羧得到α-乙酰氧基-酮，然后将其水解和氧化。

  DOI：

  10.1039/j39680002617

文献信息

• METHOD FOR PRODUCING 3-METHYL-CYCLOPENTADECENONES, METHOD FOR PRODUCING (R)- AND (S)- MUSCONE, AND METHOD FOR PRODUCING OPTICALLY ACTIVE MUSCONE
  申请人：Doya Masaharu

  公开号：US20110172465A1

  公开（公告）日：2011-07-14

  By intramolecular condensation reaction of 2,15-hexadecanedione in a gaseous phase with a compound of a Group II element of the Periodic Table as a catalyst, 3-methyl-cyclopentadecenones is generated. Magnesium oxide, calcium oxide, or zinc oxide is desirable as the catalyst for the intramolecular condensation reaction. (R)- and (S)-muscone is generated by subjecting 3-methyl-cyclopentadecenones obtained as above to hydrogenation by using a catalyst. Palladium catalyst is desirable as the hydrogenation catalyst. Optically active muscone is generated by separating 3-methyl-cyclopentadecenones into respective components thereof by means of precision distillation and subsequently subjecting the separated 3-methyl-cyclopentadecenones to asymmetric hydrogenation by using an optically active ruthenium complex catalyst. The production methods described above enable easy and economical production of 3-methyl-cyclopentadecenones, (R)- and (S)-muscone, and optically active muscone.

  通过在气相中使用周期表第二元素化合物作为催化剂，对2,15-己十二酮进行分子内缩合反应，生成3-甲基环戊十五烯酮。镁氧化物、钙氧化物或氧化锌是分子内缩合反应的理想催化剂。通过使用催化剂对上述获得的3-甲基环戊十五烯酮进行加氢反应，生成(R)-和(S)-麝香酮。钯催化剂是加氢反应的理想催化剂。通过精密蒸馏将3-甲基环戊十五烯酮分离成各自的组分，然后使用光学活性钌配合物催化剂对分离的3-甲基环戊十五烯酮进行不对称加氢反应，可以生成光学活性麝香酮。上述生产方法可实现3-甲基环戊十五烯酮、(R)-和(S)-麝香酮以及光学活性麝香酮的易于和经济的生产。
• Addition of ketones to alkenes
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP0976714A1

  公开（公告）日：2000-02-02

  The invention provides radical addition of ketone to alkene of the form: where R1 = alkyl R2 = H or alkyl n = 1 to 8 or where R3 = H or lower alkyl R4 = H or lower alkyl m = 2 to 8. The process can be used to produce precursors useful in the production of macrocyclic ketones, particularly muscone.

  该发明提供了将酮基加成到以下形式的烯烃中的基团：其中R1 = 烷基，R2 = H或烷基，n = 1到8，或其中R3 = H或低烷基，R4 = H或低烷基，m = 2到8。该方法可用于生产用于制造大环酮的前体，特别是肉麝香。
• Coated detergent tablet
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0846756A1

  公开（公告）日：1998-06-10

  The present invention relates to tablets comprising a core and a coating, the core being formed by compressing a particulate material, the particulate material comprising surfactant and detergent builder, and the tablet further comprises a disintegrant, at least some of the disintegrant being in the coating. The invention also relates to processes for making the tablets.

  本发明涉及片剂，包括片芯和包衣。 片剂还包括崩解剂，至少部分崩解剂存在于包衣中。 本发明还涉及片剂的制造工艺。
• Tablets, and process for making tablets
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0881282A1

  公开（公告）日：1998-12-02

  The invention relates to a tablet comprising a combination of a means for providing effervecency upon contact with water, as well as a soluble salt selected from the group consisting of acetate, urea, and mixtures thereof. The means for providing effervecency upon contact with water preferably comprises citric acid and a carbonate salt, such as a bicarbonate salt. A process for making tablets according to the invention is also provided.

  本发明涉及一种片剂，它由一种在与水接触时能起效的物质和一种从醋酸盐、尿素及其混合物组成的组中选出的可溶性盐组合而成。与水接触后产生药效的物质最好包括柠檬酸和碳酸盐，如碳酸氢盐。 本发明还提供了一种片剂的制造工艺。
• Fabric rejuvenating treatment
  申请人：The Procter & Gamble Company

  公开号：EP1090980A1

  公开（公告）日：2001-04-11

  The present invention is directed to a domestic process for rejuvenating an old fabric by contacting said fabric with a high dose of enzyme for an efficient period of time and subsequently contacting said fabric with an enzyme inhibitor. The present invention further relates to a rejuvenating composition for use in such process and is also directed to the manufacture of a rejuvenating composition for use in such process.

  本发明涉及一种使旧织物恢复活力的家用工艺，其方法是将所述织物与高剂量的酶接触一段时间，然后再将所述织物与酶抑制剂接触。本发明进一步涉及一种用于这种工艺的再生组合物，还涉及用于这种工艺的再生组合物的制造。