[(2R,3S,4R,5R)-3,4-dihydroxy-5-(7-methoxy-5-methylimidazo[4,5-b]pyridin-3-yl)oxolan-2-yl]methyl dihydrogen phosphate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2R,3S,4R,5R)-3,4-dihydroxy-5-(7-methoxy-5-methylimidazo[4,5-b]pyridin-3-yl)oxolan-2-yl]methyl dihydrogen phosphate
• 化学式: C₁₃H₁₈N₃O₈P
• 分子量: 375.27
• InChiKey: QOUZANXYXXOQFC-UORFTKCHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  156
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• MODIFIED POLYNUCLEOTIDES ENCODING SIAH E3 UBIQUITIN PROTEIN LIGASE 1
  申请人：Bancel Stephane

  公开号：US20140141068A1

  公开（公告）日：2014-05-22

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
• MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE
  申请人：Moderna Therapeutics, Inc.

  公开号：US20160199513A1

  公开（公告）日：2016-07-14

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS
  申请人：ModernaTX, Inc.

  公开号：US20170028085A1

  公开（公告）日：2017-02-02

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA
  申请人：ModernaTX, Inc.

  公开号：US20170252461A1

  公开（公告）日：2017-09-07

  The invention relates to compositions and methods for the manufacture and optimization of modified mRNA molecules via optimization of their terminal architecture.
• US9255129B2
  申请人：——

  公开号：US9255129B2

  公开（公告）日：2016-02-09