2-Methyl-6-[(2-methylpropan-2-yl)oxy]oxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Methyl-6-[(2-methylpropan-2-yl)oxy]oxane-3,4,5-triol
• 英文别名: 2-methyl-6-[(2-methylpropan-2-yl)oxy]oxane-3,4,5-triol
• 化学式: C₁₀H₂₀O₅
• 分子量: 220.26
• InChiKey: FFDMEZPWNOFROT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• SYNTHESIS OF CARBOHYDRATE-BASED SURFACTANTS
  申请人：THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US20140142287A1

  公开（公告）日：2014-05-22

  The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate-based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a hydrophobic compound.

  本发明提供了基于碳水化合物的表面活性剂以及生产这些表面活性剂的方法。生产基于碳水化合物的表面活性剂的方法包括使用糖基化促进剂将碳水化合物或其衍生物与疏水性化合物连接起来。
• US9499575B2
  申请人：——

  公开号：US9499575B2

  公开（公告）日：2016-11-22
• [EN] CONJUGATES OF QUATERNIZED TUBULYSIN COMPOUNDS<br/>[FR] CONJUGUÉS DE COMPOSÉS DE TUBULYSINE QUATERNISÉS
  申请人：SEATTLE GENETICS INC

  公开号：WO2017096311A1

  公开（公告）日：2017-06-08

  Compounds and compositions are disclosed in which a quaternized drug unit is linked to a targeting ligand unit from which a tertiary amine-containing drug is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease using the compounds and compositions of the invention are also disclosed.