(1S,2R,5S,7R,9R,10S,14R,15S,19S)-15-[5-(dimethylamino)-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-7-(3,4,5-trimethoxy-6-methyloxan-2-yl)oxy-20-oxatetracyclo[10.10.0.02,10.05,9]docosa-3,11-diene-13,21-dione

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1S,2R,5S,7R,9R,10S,14R,15S,19S)-15-[5-(dimethylamino)-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-7-(3,4,5-trimethoxy-6-methyloxan-2-yl)oxy-20-oxatetracyclo[10.10.0.02,10.05,9]docosa-3,11-diene-13,21-dione
• 化学式: C₄₁H₆₅NO₁₀
• 分子量: 732.0
• InChiKey: SRJQTHAZUNRMPR-MDOJQBJKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  52
• 可旋转键数：
  9
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  111
• 氢给体数：
  0
• 氢受体数：
  11

文献信息

• PARASITICIDAL COMPOUNDS, METHODS, AND FORMULATIONS
  申请人：ELI LILLY AND COMPANY

  公开号：US20160115189A1

  公开（公告）日：2016-04-28

  Provided are compounds of formula I useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier.

  提供了一些化学式I的化合物，可用于控制动物和农业中的寄生虫。还提供了一种通过向动物施用上述化合物或其药学上可接受的盐的有效量来控制动物寄生虫感染的方法，以及使用上述化合物或其可接受的盐以及可接受的载体控制寄生虫感染的配方。
• Aziridine spinosyn derivatives and methods of making
  申请人：AgriMetis, LLC

  公开号：US10570165B2

  公开（公告）日：2020-02-25

  Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-5,6 double bond to provide an aziridine ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.

  本研究提供了包括旋光花苷衍生物的组合物和生产旋光花苷衍生物的方法。本文所述的尖孢菌苷衍生物包括那些在 C-5,6 双键上官能化以提供氮丙啶环系统的衍生物。该方法生产出的尖孢菌苷衍生物对昆虫、蛛形纲动物和线虫具有活性，可用于农业和动物保健市场。
• Spinosyn derivatives as insecticides
  申请人：AGRIMETIS, LLC

  公开号：US10711026B2

  公开（公告）日：2020-07-14

  Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of spinosyn A to provide an additional ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and animal health markets.

  本研究提供了包括旋光花苷衍生物的组合物以及生产旋光花苷衍生物的方法。本文所述的旋光花苷衍生物包括在旋光花苷 A 的 C5-C6 双键上官能化以提供额外环系的旋光花苷衍生物。该方法生产出的尖孢菌苷衍生物对昆虫、蛛形纲动物和/或线虫具有活性，可用于农业和动物保健市场。
• ARTHROPOD PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS
  申请人：Ogawa Masaomi

  公开号：US20140142054A1

  公开（公告）日：2014-05-22

  Disclosed is an arthropod pest control composition having an excellent controlling effect on arthropod pests, which comprises an amide compound represented by formula (a), a spinosin compound represented by formula (1), wherein R 1 , R 2 , X 1 , X 2 are defined in the present claims, and one or more compounds selected from Group (A), consisting of fipronil, pymetrozine, a compound represented by formula (b) and a neonicotinoid compound containing a nitroguanidine structure.
• SPINOSYN DERIVATIVES AS INSECTICIDES
  申请人：AGRIMETIS, LLC

  公开号：US20190309007A1

  公开（公告）日：2019-10-10

  Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of spinosyn A to provide an additional ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and animal health markets.