2-azido-N-[(5S)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-azido-N-[(5S)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
• 化学式: C8H14N4O6
• 分子量: 262.22
• InChiKey: AFNOHTDETQTADW-KOLMUDKQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  134
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• VIRUSES MODIFIED WITH UNNATURAL MOIETIES AND METHODS OF USE THEREOF
  申请人：Carrico Isaac Sheridan

  公开号：US20140140962A1

  公开（公告）日：2014-05-22

  The invention provides compositions and methods for making and using modified viruses, including infectious viruses, having an external surface linked to at least one heterologous unnatural moiety that is exemplified by unnatural amino acid and unnatural saccharide. The unnatural moiety that is linked to the invention's modified viruses is optionally further linked to a molecule of interest (such as probe, cytotoxin, therapeutic molecule, antibody, affibody, epitope, etc. The invention's compositions and methods for use in, for example, diagnostic applications and therapeutic applications such as gene therapy, oncolytic therapy, and/or vaccine therapy.
• US8076496B2
  申请人：——

  公开号：US8076496B2

  公开（公告）日：2011-12-13