10-Methoxy-4-(6-methylpyridin-3-yl)-7-thia-2,5,9-triazatricyclo[6.4.0.02,6]dodeca-1(8),3,5,9,11-pentaene

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 10-Methoxy-4-(6-methylpyridin-3-yl)-7-thia-2,5,9-triazatricyclo[6.4.0.02,6]dodeca-1(8),3,5,9,11-pentaene
• 英文别名: 10-methoxy-4-(6-methylpyridin-3-yl)-7-thia-2,5,9-triazatricyclo[6.4.0.02,6]dodeca-1(8),3,5,9,11-pentaene
• 化学式: C₁₅H₁₂N₄OS
• 分子量: 296.3
• InChiKey: HFUUFHSGRPENOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  80.6
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Functionalized Magnetic Nanoparticles and Use in Imaging Amyloid Deposits and Neurofibrillary Tangles
  申请人：Akhtari Masoud

  公开号：US20140140932A1

  公开（公告）日：2014-05-22

  The present disclosure provides functionalized magnetic nanoparticles (MNPs) comprising a functional group that binds to β-amyloid deposits and/or neurofibrillary tangles. The present disclosure provides compositions comprising the functionalized MNPs, and methods of using the functionalized MNPs in imaging β-amyloid deposits and neurofibrillary tangles.
• FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES
  申请人：The Regents of the University of California

  公开号：US20160184461A1

  公开（公告）日：2016-06-30

  The present disclosure provides functionalized magnetic nanoparticles (MNPs) comprising a functional group that binds to β-amyloid deposits and/or neurofibrillary tangles. The present disclosure provides compositions comprising the functionalized MNPs, and methods of using the functionalized MNPs in imaging β-amyloid deposits and neurofibrillary tangles.
• US9272055B2
  申请人：——

  公开号：US9272055B2

  公开（公告）日：2016-03-01