2-Hydroxy-5-methylbenzaldehyde;pyridin-2-ylhydrazine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Hydroxy-5-methylbenzaldehyde;pyridin-2-ylhydrazine
• 英文别名: 2-hydroxy-5-methylbenzaldehyde;pyridin-2-ylhydrazine
• 化学式: C13H15N3O2
• 分子量: 245.28
• InChiKey: MTXWWQFMNLDRLW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.88
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  88.2
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• PYRIDYL HYDRAZONES FOR THE TREATMENT OF TUBERCULOSIS AND RELATED DISEASES
  申请人：TECNIMEDE-SOCIEDADE TECNICO-MEDICINAL, S.A.

  公开号：EP2922541A1

  公开（公告）日：2015-09-30
• US9593103B2
  申请人：——

  公开号：US9593103B2

  公开（公告）日：2017-03-14
• [EN] PYRIDYL HYDRAZONES FOR THE TREATMENT OF TUBERCULOSIS AND RELATED DISEASES<br/>[FR] PYRIDYL-HYDRAZONES POUR LE TRAITEMENT DE LA TUBERCULOSE ET DE MALADIES ASSOCIÉES
  申请人：TECNIMEDE SOCIEDADE TECNICO MEDICINAL S A

  公开号：WO2014081324A1

  公开（公告）日：2014-05-30

  The invention provides pyridyl-hydfazones of Formula I, or pharmaceutically acceptable salts, esters, solvates, isprriers and prodrugs thereof as well as pharmaceutical compositions containing these compounds for use in the prophylactic and/or therapeutic treatment of tuberculosis and related diseases, such as, diseases caused by nontuberculous mycobacteria and/or caused by Micobacterium leprae.