(2R,3S,4R,5S)-2-[2-[dimethyl(methylidene)-lambda5-phosphanyl]ethyl]-4,5-dimethyloxolan-3-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4R,5S)-2-[2-[dimethyl(methylidene)-lambda5-phosphanyl]ethyl]-4,5-dimethyloxolan-3-ol
• 英文别名: (2R,3S,4R,5S)-2-[2-[dimethyl(methylidene)-λ5-phosphanyl]ethyl]-4,5-dimethyloxolan-3-ol
• 化学式: C₁₁H₂₃O₂P
• 分子量: 218.27
• InChiKey: DMRNYAXRHGTDFS-MMWGEVLESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH BLOOD AND LYMPHATIC DISORDERS
  申请人：Bancel Stephane

  公开号：US20140147432A1

  公开（公告）日：2014-05-29

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• MODIFIED POLYNUCLEOTIDES FOR TREATING DOLICHYL-PHOSPHATE (UDP-N-ACETYLGLUCOSAMINE) N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE 1 (GLCNAC-1-P TRANSFERASE) PROTEIN DEFICIENCY
  申请人：Moderna Therapeutics, Inc.

  公开号：US20140179771A1

  公开（公告）日：2014-06-26

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• US9220755B2
  申请人：——

  公开号：US9220755B2

  公开（公告）日：2015-12-29