[3-Hydroxy-2-[[4-(3-hydroxydodecanoyloxy)-6-(hydroxymethyl)-3-methyl-5-phosphonooxyoxan-2-yl]oxymethyl]-6-[hydroxy-[hydroxy(propoxy)phosphoryl]oxyphosphoryl]oxy-5-methyloxan-4-yl] 3-hydroxydodecanoate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [3-Hydroxy-2-[[4-(3-hydroxydodecanoyloxy)-6-(hydroxymethyl)-3-methyl-5-phosphonooxyoxan-2-yl]oxymethyl]-6-[hydroxy-[hydroxy(propoxy)phosphoryl]oxyphosphoryl]oxy-5-methyloxan-4-yl] 3-hydroxydodecanoate
• 英文别名: [3-hydroxy-2-[[4-(3-hydroxydodecanoyloxy)-6-(hydroxymethyl)-3-methyl-5-phosphonooxyoxan-2-yl]oxymethyl]-6-[hydroxy-[hydroxy(propoxy)phosphoryl]oxyphosphoryl]oxy-5-methyloxan-4-yl] 3-hydroxydodecanoate
• 化学式: C₄₁H₇₉O₂₂P₃
• 分子量: 1017.0
• InChiKey: OKQQJTNEUORVII-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  66
• 可旋转键数：
  37
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  330
• 氢给体数：
  8
• 氢受体数：
  22

文献信息

• PROCESS FOR DETERGENT-FREE PRODUCTION OF OUTER MEMBRANE VESICLES OF A GRAM-NEGATIVE BACTERIUM
  申请人：Van De Waterbeemd Bas

  公开号：US20140147469A1

  公开（公告）日：2014-05-29

  The present invention relates to the fields of medical microbiology and vaccines. In particular the invention relates to a process for detergent-free preparation of outer membrane vesicles (OMV) of Gram negative bacteria for use in vaccines, to OMV obtainable by said process, and to a pharmaceutical composition comprising such OMV. The present invention further relates to the use of OMV of the present invention as a medicament in particular for use in a method for eliciting an immune response.
• US9272006B2
  申请人：——

  公开号：US9272006B2

  公开（公告）日：2016-03-01