N-((5-acrylamido-3,4,6-trihydroxytetrahydro-2H-pyran-2-yl)methyl)methacrylamide | 1612145-35-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-((5-acrylamido-3,4,6-trihydroxytetrahydro-2H-pyran-2-yl)methyl)methacrylamide
• 英文别名: 2-methyl-N-[[3,4,6-trihydroxy-5-(prop-2-enoylamino)oxan-2-yl]methyl]prop-2-enamide
• CAS: 1612145-35-3
• 化学式: C₁₃H₂₀N₂O₆
• 分子量: 300.312
• InChiKey: FAQSSAKEHADQRN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  128
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• HIGH PERFORMANCE ACRYLAMIDE ADHESIVES
  申请人：Empire Technology Development LLC

  公开号：US20140155563A1

  公开（公告）日：2014-06-05

  Disclosed are derivatives of (tetrahydropyranyl)methyl acrylamide and polymers derived therefrom, as well as methods of making such compounds and polymers. Adhesives, coatings, and plastics which include such polymers are also described.

  本发明涉及（四氢吡喃基）甲基丙烯酰胺的衍生物及其衍生的聚合物，以及制备这些化合物和聚合物的方法。还描述了包括这种聚合物的粘合剂、涂料和塑料。
• ACRYLAMIDE HYDROGELS FOR TISSUE ENGINEERING
  申请人：Carlson William B.

  公开号：US20140178344A1

  公开（公告）日：2014-06-26

  Disclosed are acrylamide hydrogels prepared from derivatives of (tetrahydropyranyl)methyl- and (tetrahydrofuranyl)methyl-acrylamide, methods of making the same, and methods of wound healing or tissue generation with acrylamide hydrogels.
• US9212245B2
  申请人：——

  公开号：US9212245B2

  公开（公告）日：2015-12-15
• [EN] HIGH PERFORMANCE ACRYLAMIDE ADHESIVES<br/>[FR] ADHÉSIFS EN ACRYLAMIDE À HAUTES PERFORMANCES
  申请人：EMPIRE TECHNOLOGY DEV LLC

  公开号：WO2014088555A1

  公开（公告）日：2014-06-12

  Disclosed are derivatives of (tetrahydropyranyl)methyl acrylamide and polymers derived therefrom, as well as methods of making such compounds and polymers. Adhesives, coatings, and plastics which include such polymers are also described.
• [EN] ACRYLAMIDE HYDROGELS FOR TISSUE ENGINEERING<br/>[FR] HYDROGELS D'ACRYLAMIDE POUR L'INGÉNIERIE TISSULAIRE
  申请人：EMPIRE TECHNOLOGY DEV LLC

  公开号：WO2014088557A1

  公开（公告）日：2014-06-12

  The present technology provides acrylamide hydro gels which may be used as scaffold materials in numerous applications including, but not limited to, wound healing, tissue regeneration and engineering, artificial organ growth, and cartilage repair. In this regard, the acrylamide hydrogels can be used as scaffold materials in vivo to aid in the vascularization and creation of new tissues, the repair of wounded tissue, and to replace non-functional tissues. The hydrogels include may be prepared from inexpensive and renewable resources such as furanose and pyranose sugars and derivatives thereof using practical and scalable methods. The non-toxic biodegradation products from the acrylamide hydrogelssugars and sugar-like derivatives-are fully compatible with, and may be metabolized by, living systems, thus eliminating in vivo toxicity and autoimmune response concerns associated with existing hydrogel scaffolds. Being comprised of sugar and sugar-like derivatives, the present hydrogels may also find use as cell culture media.