5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxyoxolan-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxyoxolan-2-one
• 化学式: C₈H₁₄O₆
• 分子量: 206.19
• InChiKey: MWGIJLUNXVJTFG-DPIDSQGUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  96.2
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Composition for Stabilizing Ascorbic Acid Derivatives and the Application Thereof
  申请人：CORUM INC.

  公开号：US20140155633A1

  公开（公告）日：2014-06-05

  This invention discloses a composition for stabilizing ascorbic acid derivative and the application thereof. The mentioned composition comprises ascorbic acid derivative, buffer, phosphonic acid derivative and at least one alcohol. The yellowish and degradation of ascorbic acid derivative can be efficiently decreased by the mentioned composition. Moreover, the mentioned composition can be used in topical composition, such as toner, serum, lotion, cream.
• Method for Stabilizing Ascorbic Acid Derivatives and the Application Thereof
  申请人：CORUM INC.

  公开号：US20160136078A1

  公开（公告）日：2016-05-19

  This invention discloses a method for stabilizing ascorbic acid derivatives and the application thereof. The mentioned method comprises mixing ascorbic acid derivative with a non-water-in-oil composition, and the composition comprises buffer, phosphonic acid derivative and at least one alcohol. The yellowish and degradation of ascorbic acid derivative can be efficiently decreased by the mentioned method. Moreover, the mentioned method can be used in topical composition, such as toner, serum, lotion, cream.