(2R,3S,4S,5R)-2,3,4,5-tetrahydroxyhexanamide;hydrochloride

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4S,5R)-2,3,4,5-tetrahydroxyhexanamide;hydrochloride
• 化学式: C6H14ClNO5
• 分子量: 215.63
• InChiKey: YYCVEPVRDLLFNT-FLGKMABCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.64
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  124
• 氢给体数：
  6
• 氢受体数：
  5

文献信息

• [EN] ACRYLAMIDE HYDROGELS FOR TISSUE ENGINEERING<br/>[FR] HYDROGELS D'ACRYLAMIDE POUR L'INGÉNIERIE TISSULAIRE
  申请人：EMPIRE TECHNOLOGY DEV LLC

  公开号：WO2014088557A1

  公开（公告）日：2014-06-12

  The present technology provides acrylamide hydro gels which may be used as scaffold materials in numerous applications including, but not limited to, wound healing, tissue regeneration and engineering, artificial organ growth, and cartilage repair. In this regard, the acrylamide hydrogels can be used as scaffold materials in vivo to aid in the vascularization and creation of new tissues, the repair of wounded tissue, and to replace non-functional tissues. The hydrogels include may be prepared from inexpensive and renewable resources such as furanose and pyranose sugars and derivatives thereof using practical and scalable methods. The non-toxic biodegradation products from the acrylamide hydrogelssugars and sugar-like derivatives-are fully compatible with, and may be metabolized by, living systems, thus eliminating in vivo toxicity and autoimmune response concerns associated with existing hydrogel scaffolds. Being comprised of sugar and sugar-like derivatives, the present hydrogels may also find use as cell culture media.