[(2R,3S,4S,5S,6S)-2-(azidomethyl)-3,4,5,6-tetrahydroxyoxan-2-yl]-phosphonooxyphosphinic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2R,3S,4S,5S,6S)-2-(azidomethyl)-3,4,5,6-tetrahydroxyoxan-2-yl]-phosphonooxyphosphinic acid
• 化学式: C6H13N3O11P2
• 分子量: 365.13
• InChiKey: VZIUZOXESRYYSL-GKFJPSPNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  209
• 氢给体数：
  7
• 氢受体数：
  13

文献信息

• D-amino acid derivative-modified peptidoglycan and methods of use thereof
  申请人：The Regents of the University of California

  公开号：US10016498B2

  公开（公告）日：2018-07-10

  The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker.

  本公开提供了包含改性 D-氨基酸的改性细菌和改性肽聚糖；包含改性细菌或肽聚糖的组合物；以及使用改性细菌或肽聚糖的方法。改性 D-氨基酸包括生物正交官能团，如叠氮基、炔基或降冰片烯基。还提供了通过连接体与相关分子共轭的改性肽聚糖。
• D-Amino Acid Derivative-Modified Peptidoglycan and Methods of Use Thereof
  申请人：The Regents of the University of California

  公开号：US20140170183A1

  公开（公告）日：2014-06-19

  The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker.
• D-AMINO ACID DERIVATIVE-MODIFIED PEPTIDOGLYCAN AND METHODS OF USE THEREOF
  申请人：The Regents of the University of California

  公开号：US20170021013A1

  公开（公告）日：2017-01-26

  The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker.
• US9303068B2
  申请人：——

  公开号：US9303068B2

  公开（公告）日：2016-04-05
• US9789180B2
  申请人：——

  公开号：US9789180B2

  公开（公告）日：2017-10-17