2-Ethoxy-3-[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]pentanoic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Ethoxy-3-[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]pentanoic acid
• 英文别名: 2-ethoxy-3-[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]pentanoic acid
• 化学式: C₂₂H₂₆O₆
• 分子量: 386.4
• InChiKey: KZHMQDRSCFZPBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  28
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE AND OTHER METABOLIC DISEASES
  申请人：METABOLIC SOLUTIONS DEVELOPMENT COMPANY LLC

  公开号：US20160051529A1

  公开（公告）日：2016-02-25

  The present invention relates to PPARy-sparing compounds and pharmaceutical compositions formulated with such compounds that are useful for treating, delaying the onset of, or reducing the symptoms of a neurodegenerative disorder including Huntington's disease, epilepsy, AMS, and MS.

  本发明涉及PPARy-sparing化合物和与这些化合物配制的药物组合物，其可用于治疗、延缓或减轻神经退行性疾病的症状，包括亨廷顿病、癫痫、AMS和MS。
• PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
  申请人：Metabolic Solutions Development Company, LLC

  公开号：EP2931274A1

  公开（公告）日：2015-10-21
• [EN] PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES<br/>[FR] THIAZOLIDINEDIONES ÉPARGNANT LES PPAR ET ASSOCIATIONS POUR LE TRAITEMENT DE MALADIES NEURODÉGÉNÉRATIVES
  申请人：METABOLIC SOLUTIONS DEV CO LLC

  公开号：WO2014093114A1

  公开（公告）日：2014-06-19

  The present invention relates to PPARy- sparing compounds and pharmaceutical compositions formulated with such compounds that are useful for treating, delaying the onset of, or reducing the symptoms of a neurodegenerative disorder including Huntington's disease, epilepsy, AMS, and MS.