2-Methyl-3-propoxybuta-1,3-diene

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Methyl-3-propoxybuta-1,3-diene
• 英文别名: 2-methyl-3-propoxybuta-1,3-diene
• 化学式: C₈H₁₄O
• 分子量: 126.2
• InChiKey: TXWMEGDYCQVHGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] BLOCK COPOLYMERS AND THEIR CONJUGATES OR COMPLEXES WITH OLIGONUCLEOTIDES<br/>[FR] COPOLYMÈRES SÉQUENCÉS ET LEUR CONJUGUÉS OU COMPLEXES AVEC DES OLIGONUCLÉOTIDES
  申请人：PHASERX INC

  公开号：WO2015017519A1

  公开（公告）日：2015-02-05

  Described herein are block copolymers, and methods of making and utilizing such copolymers. The described block copolymers are disruptive of a cellular membrane, including an extracellular membrane, an intracellular membrane, a vesicle, an organelle, an endosome, a liposome, or a red blood cell. Preferably, in certain instances, the block copolymer disrupts the membrane and enters the intracellular environment. In specific examples, the block copolymer is endosomolytic and capable of delivering an oligonucleotide (e.g., an mRNA) to a cell. Compositions comprising a block copolymer and an oligonucleotide (e.g., an mRNA) are also disclosed.

  本文描述了嵌段共聚物以及制备和利用这种共聚物的方法。所述的嵌段共聚物破坏细胞膜，包括细胞外膜、细胞内膜、囊泡、细胞器、内体、脂质体或红细胞。在某些情况下，该嵌段共聚物会破坏膜并进入细胞内环境。在具体示例中，该嵌段共聚物具有内体溶解作用，并能够将寡核苷酸（例如mRNA）传递到细胞中。还公开了包含嵌段共聚物和寡核苷酸（例如mRNA）的组合物。
• HYDROPHILIC-OLEOPHOBIC COPOLYMER COMPOSITION AND USES THEREOF
  申请人：General Electric Company

  公开号：US20150136712A1

  公开（公告）日：2015-05-21

  Provided herein are copolymers and copolymer compositions that are both hydrophilic and oleophobic. The copolymers include structural units derived from a fluoroalkyl monomer and a zwitterionic monomer. It further relates to membranes formed by coating a porous substrate with the copolymeric compositions. The copolymeric coating imparts hydrophilicity and oleophobicity/oil-tolerance to the membranes. The uses of such membranes as microfiltration membrane or ultrafiltration membrane are also provided.
• TRIAZINE MEDIATED LIVING RADICAL CONTROLLED POLYMERIZATION
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：US20160311785A1

  公开（公告）日：2016-10-27

  The disclosure provides modular triazine-based unimolecular initiator compounds useful in controlled radical polymerizations of vinyl-containing monomers.
• [EN] FLUORESCENCE DETECTOR SYSTEM FOR DETECTION OF AN AROMATIC HYDROCARBON<br/>[FR] SYSTÈME DÉTECTEUR À FLUORESCENCE POUR LA DÉTECTION D'UN HYDROCARBURE AROMATIQUE
  申请人：TNO

  公开号：WO2014092576A1

  公开（公告）日：2014-06-19

  The invention relates to a detector system suitable for detection of an aromatic hydrocarbon, comprising an organic polymeric sensor material that is permeable to the aromatic hydrocarbon, the sensor material comprising a molecular probe selected from the group of methanatoboron moieties. Further, the invention relates to the use of a detector system according to the invention for the detection of an aromatic hydrocarbon, preferably an aromatic hydrocarbon selected from the group of benzene, toluene and xylene.