methyl (4R,5R)-5-amino-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl (4R,5R)-5-amino-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
• 化学式: C₁₀H₁₉NO₈
• 分子量: 281.26
• InChiKey: HFIMWQWKLKRXKD-XNNAWXANSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.4
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  163
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• Factor IX: Remodeling and Glycoconjugation of Factor IX
  申请人：Novo Nordisk A/S

  公开号：US20140170728A1

  公开（公告）日：2014-06-19

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS
  申请人：Novo Nordisk A/S

  公开号：US20150343080A1

  公开（公告）日：2015-12-03

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII
  申请人：Novo Nordisk A/S

  公开号：US20160193353A1

  公开（公告）日：2016-07-07

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• US8076292B2
  申请人：——

  公开号：US8076292B2

  公开（公告）日：2011-12-13