2-[2-(1-Hydroxy-2-oxoethoxy)-3-methyl-4-oxobutoxy]acetic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-(1-Hydroxy-2-oxoethoxy)-3-methyl-4-oxobutoxy]acetic acid
• 英文别名: 2-[2-(1-hydroxy-2-oxoethoxy)-3-methyl-4-oxobutoxy]acetic acid
• 化学式: C₉H₁₄O₇
• 分子量: 234.2
• InChiKey: AOJICEGJFDPJGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  16
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  110
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• LIQUID EMBOLIC MATERIAL INCLUDING CARBOXYMETHYL CHITOSAN CROSSLINKED WITH CARBOXYMETHYL CELLULOSE
  申请人：REGENTS OF THE UNIVERSITY OF MINNESOTA

  公开号：US20140171907A1

  公开（公告）日：2014-06-19

  A liquid embolic material may include a mixture of a first solution comprising between about 1.2% and about 2.5% weight per volume (w/v) carboxymethyl chitosan (CCN) in a first solvent and a second solution comprising between about 1.2% and about 2.5% w/v oxidized carboxymethyl cellulose (OCMC) in a second solvent. The liquid embolic material may be used to embolize a targeted embolization location by mixing the first solution and the second solution to form a liquid embolic material (or hydrogel precursor material), introducing the hydrogel precursor material to a targeted embolization location within a body of a patient, and allowing the CCN and the OCMC to react to form the hydrogel material and embolize the targeted embolization location.
• US8936795B2
  申请人：——

  公开号：US8936795B2

  公开（公告）日：2015-01-20