(4S)-4-[1-aminoethyl-[(2R)-2-aminopropyl]amino]pentan-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4S)-4-[1-aminoethyl-[(2R)-2-aminopropyl]amino]pentan-2-one
• 化学式: C₁₀H₂₃N₃O
• 分子量: 201.31
• InChiKey: POZSOWDLDJGQBC-HHCGNCNQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  72.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• MACROMOLECULES
  申请人：Owen David

  公开号：US20140171375A1

  公开（公告）日：2014-06-19

  The present invention relates to a macromolecule comprising a dendrimer having surface amino groups to which at least two different terminal groups are attached including a pharmaceutically active agent and a pharmacokinetic modifying agent, the pharmaceutically active agent comprising a hydroxyl group and being attached to the surface amino group of the dendrimer through a diacid linker. Pharmaceutical compositions comprising the macromolecules and methods of treatment using the macromolecules are also described.
• US9744246B2
  申请人：——

  公开号：US9744246B2

  公开（公告）日：2017-08-29