(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-12-[(4S,5S,6S)-5-[(4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',6',11,13,22-pentamethyl-2-methylidenespiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-21,24-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-12-[(4S,5S,6S)-5-[(4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',6',11,13,22-pentamethyl-2-methylidenespiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-21,24-diol
• 化学式: C₄₆H₇₀O₁₃
• 分子量: 831.0
• InChiKey: LBSVWSJTWSHLDT-IFQBKPLDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  59
• 可旋转键数：
  6
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  153
• 氢给体数：
  3
• 氢受体数：
  13

文献信息

• [EN] INJECTABLE EPRINOMECTIN FORMULATION AND ANTHELMINTIC USE THEREOF<br/>[FR] FORMULATION D'ÉPRINOMECTINE INJECTABLE ET UTILISATION ANTHELMINTIQUE DE CELLE-CI
  申请人：ALLEVA ANIMAL HEALTH LTD

  公开号：WO2014098623A1

  公开（公告）日：2014-06-26

  A method of treating a herd of cattle in a milking shed by injecting an animal at an injection site at or near the rear of the animal with an anthelmintic injectable formulation comprising eprinomectin dissolved in an organic solvent. The injections can be applied at positions X of a rotary milking shed whilst the cows are in their bails on the rotary platform. Injection positions for a herringbone milking shed are also described and illustrated. The injectable formulation has a nil milk withholding time so that it can be used on lactating cows.