(3R,4S,6S)-5-amino-6-[(3R,4S)-5-amino-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-2-(hydroxymethyl)oxane-3,4-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3R,4S,6S)-5-amino-6-[(3R,4S)-5-amino-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-2-(hydroxymethyl)oxane-3,4-diol
• 化学式: C₁₂H₂₄N₂O₈
• 分子量: 324.33
• InChiKey: DNYLJXXVQKKVEV-VEDQSETESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  181
• 氢给体数：
  7
• 氢受体数：
  10

文献信息

• Chitosan -Amelogenin Hydrogel for In Situ Enamel Growth
  申请人：University of Southern California

  公开号：US20140186273A1

  公开（公告）日：2014-07-03

  A composition for re-constructing enamel-coated substrates such as a tooth which includes an amelogenin, chitosan, and water. The composition may also include compounds providing calcium and phosphate ions. Methods using the composition are also provided.
• GLUCOSE-SENSITIVE NANOPARTICLE FOR CANCER DIAGNOSIS AND THERAPY
  申请人：INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY

  公开号：US20150374828A1

  公开（公告）日：2015-12-31

  Disclosed are glucose-sensitive nanoparticles which includes a phenylboronic acid derivative and a biocompatible polymer, and is prepared as an amphiphilic conjugate having chemical binding between the phenylboronic acid derivative and the biocompatible polymer. The use of the composition can effectively collect glucose in the cancer tissue, thereby simultaneously performing diagnosis and therapy of cancer.
• AMELOGENIN-CHITOSAN HYDROGEL FOR DENTIN HYPERSENSITIVITY
  申请人：UNIVERSITY OF SOUTHERN CALIFORNIA

  公开号：US20170007737A1

  公开（公告）日：2017-01-12

  A method to regrow a protective layer over exposed/demineralized dentin that includes a step of identifying a subject having exposed/demineralized dentin. The demineralized dentin is contacted with a remineralization composition that includes an amelogenin and derived peptides, a chitosan, water, and a sufficient amount of a pH adjusting component such that the composition has a pH greater than about 6.0 such that dentinal tubules are occluded with apatite crystals and enamel is regrown on the dentinal tubules.
• Delayed-Release Particles
  申请人：The Procter & Gamble Company

  公开号：US20170362543A1

  公开（公告）日：2017-12-21

  A delayed-release particle comprising a polymer-based matrix comprising polyvinylpyrrolidone and chitosan, and a hydrophobic benefit agent encapsulated by said polymer-based matrix; and processes and consumer products related thereto.
• US9557332B2
  申请人：——

  公开号：US9557332B2

  公开（公告）日：2017-01-31