(2-hydroxyacetyl) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2-hydroxyacetyl) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
• 化学式: C₈H₁₄O₉
• 分子量: 254.19
• InChiKey: BUWHDPWRFREPMT-XYXSHXKPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• HUMAN CYTOMEGALOVIRUS NEUTRALIZING ANTIBODIES AND USE THEREOF
  申请人：INSTITUTE FOR RESEARCH IN BIOMEDICINE

  公开号：US20140193428A1

  公开（公告）日：2014-07-10

  The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, prevention, and therapy of disease.