2-Methoxy-4-(4-methoxy-2,4-dimethylpentan-2-yl)oxy-2,4-dimethylpentane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Methoxy-4-(4-methoxy-2,4-dimethylpentan-2-yl)oxy-2,4-dimethylpentane
• 英文别名: 2-methoxy-4-(4-methoxy-2,4-dimethylpentan-2-yl)oxy-2,4-dimethylpentane
• 化学式: C₁₆H₃₄O₃
• 分子量: 274.44
• InChiKey: PVLCRPKVMABSKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] BIVALENT ANTAGONISTS OF INHIBITORS OF APOPTOSIS PROTEINS<br/>[FR] ANTAGONISTES BIVALENTS D'INHIBITEURS DE PROTÉINES D'APOPTOSE
  申请人：HEPAGENE THERAPEUTICS HK LTD

  公开号：WO2020206000A1

  公开（公告）日：2020-10-08

  The present technology is directed to compounds, compositions, and methods related to treatment of cancers and viral infections mediated by IAPs, e.g., compounds of Formula I (including Formulas IA, IB, IC, ID, IE, IF, and IG), a stereoisomer thereof, or a pharmaceutically acceptable salt of the compound or the stereoisomer of the compound. In particular, the present compounds and compositions may be used to treat IAP-mediated ovarian cancer and hepatitis B infection.

  目前的技术是针对由IAP介导的癌症和病毒感染的化合物、组合物和治疗方法，例如Formula I（包括Formula IA、IB、IC、ID、IE、IF和IG）、其立体异构体，或该化合物或其立体异构体的药用盐。具体来说，目前的化合物和组合物可用于治疗IAP介导的卵巢癌和乙型肝炎感染。
• [EN] DIMERIC PEPTIDE INHIBITORS OF APOPTOSIS PROTEINS<br/>[FR] INHIBITEURS PEPTIDIQUES DIMÈRES DE PROTÉINES D'APOPTOSE
  申请人：HEPAGENE THERAPEUTICS INC

  公开号：WO2019023275A1

  公开（公告）日：2019-01-31

  The present technology is directed to compounds, compositions, and methods related to treatment of cancers and viral infections mediated by lAPs. In particular the present compounds and compositions may be used to treat lAP-mediated ovarian cancer and hepatitis B infection.

  现有技术涉及到与治疗lAPs介导的癌症和病毒感染有关的化合物、组合物和方法。特别是，现有的化合物和组合物可用于治疗lAP介导的卵巢癌和乙型肝炎感染。
• Polymer-Agent Conjugates, Particles, Compositions, and Related Methods of Use
  申请人：CERULEAN PHARMA INC.

  公开号：US20140193510A1

  公开（公告）日：2014-07-10

  Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.

  本文描述了聚合物-药物共轭物和颗粒，可用于例如癌症治疗。本文还描述了包含这些颗粒的混合物、组合物和剂型，使用这些颗粒的方法（例如，治疗某种疾病），包括聚合物-药物共轭物和颗粒的工具箱，制备聚合物-药物共轭物和颗粒的方法，储存颗粒的方法和分析颗粒的方法。