1,1,1-Trifluoro-3-[2-(3,3,3-trifluoropropoxy)ethoxy]propane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1,1-Trifluoro-3-[2-(3,3,3-trifluoropropoxy)ethoxy]propane
• 英文别名: 1,1,1-trifluoro-3-[2-(3,3,3-trifluoropropoxy)ethoxy]propane
• 化学式: C₈H₁₂F₆O₂
• 分子量: 254.17
• InChiKey: NYSMHFOTBJGHNX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• ORGANIC SYNTHESIS APPLICATIONS OF NON-AQUEOUS FLUORIDE SALT SOLUTIONS
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20170057908A1

  公开（公告）日：2017-03-02

  Processes and reaction mixtures including non-aqueous solvent mixtures are presented. Non-aqueous solvent mixtures including fluoride salt and non-aqueous solvent combinations are provided that possess high fluoride ion concentrations useful for a range of applications, including organic synthesis. Further non-aqueous solvent mixtures are provided including a salt possessing a non-fluoride anion and a non-aqueous solvent that, when contacted with aqueous fluoride-containing reagents, extract fluoride ions to form non-aqueous fluoride-ion solutions possessing high fluoride-ion concentrations. The salts include an organic cation that does not possess a carbon in the β-position or does not possess a carbon in the β-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2-dimethylpropyl)dimethylammonium fluoride. The combination of these fluoride salts with at least one fluorine-containing non-aqueous solvent (e.g., bis(2,2,2-trifluoroethyl)ether; (BTFE)) promotes solubility of the salt within the non-aqueous solvents.

  提供了包括非水溶剂混合物的过程和反应混合物。提供了包括氟化物盐和非水溶剂组合的非水溶剂混合物，其具有高氟离子浓度，可用于一系列应用，包括有机合成。还提供了包括具有非氟离子的盐和非水溶剂的非水溶剂混合物，当与含氟化物的水溶试剂接触时，提取氟离子以形成具有高氟离子浓度的非水溶性氟离子溶液。这些盐包括一个有机阳离子，该阳离子在β位不含碳或在β位含有结合氢的碳。这种盐的结构有助于使其在无水条件下不分解。例如，无水氟化物盐包括(2,2-二甲基丙基)三甲基铵氟化物和双(2,2-二甲基丙基)二甲基铵氟化物。这些氟化物盐与至少一种含氟非水溶剂（例如双(2,2,2-三氟乙基)醚；(BTFE)）的组合促进了盐在非水溶剂中的溶解度。
• Organic synthesis applications of non-aqueous fluoride salt solutions
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US10468722B2

  公开（公告）日：2019-11-05

  Processes and reaction mixtures including non-aqueous solvent mixtures are presented. Non-aqueous solvent mixtures including fluoride salt and non-aqueous solvent combinations are provided that possess high fluoride ion concentrations useful for a range of applications, including organic synthesis. Further non-aqueous solvent mixtures are provided including a salt possessing a non-fluoride anion and a non-aqueous solvent that, when contacted with aqueous fluoride-containing reagents, extract fluoride ions to form non-aqueous fluoride-ion solutions possessing high fluoride-ion concentrations. The salts include an organic cation that does not possess a carbon in the β-position or does not possess a carbon in the β-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2-dimethylpropyl)dimethylammonium fluoride. The combination of these fluoride salts with at least one fluorine-containing non-aqueous solvent (e.g., bis(2,2,2-trifluoroethyl)ether; (BTFE)) promotes solubility of the salt within the non-aqueous solvents.

  介绍了包括非水溶剂混合物在内的工艺和反应混合物。非水溶剂混合物包括氟化盐和非水溶剂组合，具有高氟离子浓度，可用于包括有机合成在内的一系列应用。本发明还提供了非水溶剂混合物，包括具有非氟阴离子的盐和非水溶剂，当与含氟水性试剂接触时，可萃取氟离子，形成具有高氟离子浓度的非水氟离子溶液。这些盐包括一种有机阳离子，该阳离子在 β 位不含碳，或者在 β 位不含与氢结合的碳。这种盐的结构使其能够在不分解的情况下制成无水盐。无水氟化物盐的例子包括（2,2-二甲基丙基）三甲基氟化铵和双(2,2-二甲基丙基)二甲基氟化铵。将这些氟化物盐与至少一种含氟非水溶剂（如双（2,2,2-三氟乙基）醚）结合使用，可提高盐在非水溶剂中的溶解度。
• Non-aqueous fluoride salts, solutions, and their uses
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US10720666B2

  公开（公告）日：2020-07-21

  Electrolyte solutions including at least one anhydrous fluoride salt and at least one non-aqueous solvent are presented. The fluoride salt includes an organic cation having a charge center (e.g., N, P, S, or O) that does not possess a carbon in the β-position or does not possess a carbon in the β-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2-dimethylpropyl)dimethylammonium fluoride. Combining these fluoride salts with at least one fluorine-containing non-aqueous solvent (e.g., bis(2,2,2-trifluoroethyl)ether; (BTFE)) promotes solubility of the salt within the non-aqueous solvents. The solvent may be a mixture of at least one non-aqueous, fluorine-containing solvent and at least one other non-aqueous, fluorine or non-fluorine containing solvent (e.g., BTFE and propionitrile or dimethoxyethane). The electrolyte solutions may be employed in electrochemical cells, such as batteries, fuel cells, electrolysis systems, and capacitors.

  电解质溶液包括至少一种无水氟化盐和至少一种非水溶剂。氟化盐包括一个有机阳离子，该阳离子具有一个电荷中心（如 N、P、S 或 O），该电荷中心在 β 位上不含碳，或者在 β 位上不含与氢结合的碳。这种盐的结构使其能够在不分解的情况下制成无水盐。无水氟化物盐的例子包括（2,2-二甲基丙基）三甲基氟化铵和双(2,2-二甲基丙基)二甲基氟化铵。将这些氟化物盐与至少一种含氟的非水溶剂（如双（2,2,2-三氟乙基）醚）结合，可提高盐在非水溶剂中的溶解度。溶剂可以是至少一种非水、含氟溶剂和至少一种其他非水、含氟或不含氟溶剂（如 BTFE 和丙腈或二甲氧基乙烷）的混合物。电解质溶液可用于电化学电池，如电池、燃料电池、电解系统和电容器。
• NON-AQUEOUS FLUORIDE SALTS, SOLUTIONS, AND THEIR USES
  申请人：California Institute of Technology

  公开号：EP3332442B1

  公开（公告）日：2020-07-22
• [EN] ORGANIC SYNTHESIS APPLICATIONS OF NON-AQUEOUS FLUORIDE SALT SOLUTIONS<br/>[FR] APPLICATIONS DE SYNTHÈSE ORGANIQUE DE SOLUTIONS DE SEL DE FLUORURE NON AQUEUSES
  申请人：CALIFORNIA INST OF TECHN

  公开号：WO2017069834A2

  公开（公告）日：2017-04-27

  Processes and reaction mixtures including non-aqueous solvent mixtures are presented. Non-aqueous solvent mixtures including fluoride salt and non-aqueous solvent combinations are provided that possess high fluoride ion concentrations useful for a range of applications, including organic synthesis. Further non-aqueous solvent mixtures are provided including a salt possessing a non-fluoride anion and a non-aqueous solvent that, when contacted with aqueous fluoride-containing reagents, extract fluoride ions to form non-aqueous fluoride-ion solutions possessing high fluoride-ion concentrations. The salts include an organic cation that does not possess a carbon in the β-position or does not possess a carbon in the β-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2- dimethylpropyl)dimethylammonium fluoride. The combination of these fluoride salts with at least one fluorine-containing non-aqueous solvent (e.g., bis(2,2,2-trifluoroethyl)ether; (BTFE)) promotes solubility of the salt within the non-aqueous solvents.