(3S)-3-[[4-[3-[6-[[2-[2-[2-(4-isothiocyanatobutylcarbamothioylamino)ethoxy]ethoxy]acetyl]amino]hexanoylamino]propoxy]benzoyl]amino]-4-[4-[3-[(6-methylpyridin-2-yl)amino]propoxy]phenyl]butanoic acid

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 石蒜科生物碱
• 英文名称: (3S)-3-[[4-[3-[6-[[2-[2-[2-(4-isothiocyanatobutylcarbamothioylamino)ethoxy]ethoxy]acetyl]amino]hexanoylamino]propoxy]benzoyl]amino]-4-[4-[3-[(6-methylpyridin-2-yl)amino]propoxy]phenyl]butanoic acid
• 化学式: C₄₇H₆₆N₈O₉S₂
• 分子量: 951.2
• InChiKey: SCTRLQXMVNEMLF-KDXMTYKHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  66
• 可旋转键数：
  36
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.51
• 拓扑面积：
  287
• 氢给体数：
  7
• 氢受体数：
  14

文献信息

• FUNCTIONALIZED RGD PEPTIDOMIMETICS AND THEIR MANUFACTURE, AND IMPLANT HAVING A COATING CONTAINING SUCH FUNCTIONAL-IZED RGD PEPTIDOMIMETICS
  申请人：BIOTRONIK AG

  公开号：US20140222134A1

  公开（公告）日：2014-08-07

  At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method.
• US8961592B2
  申请人：——

  公开号：US8961592B2

  公开（公告）日：2015-02-24