(2R,4S,5S)-5-[(2S,4S,5S)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2-methylpropan-2-yl)oxy]oxan-2-yl]oxy-6-(hydroxymethyl)-2-[3-(pyridin-3-ylmethoxyamino)propoxy]oxane-3,4-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,4S,5S)-5-[(2S,4S,5S)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2-methylpropan-2-yl)oxy]oxan-2-yl]oxy-6-(hydroxymethyl)-2-[3-(pyridin-3-ylmethoxyamino)propoxy]oxane-3,4-diol
• 化学式: C₂₅H₄₂N₂O₁₂
• 分子量: 562.6
• InChiKey: GOJABOMHVNBNSS-BWNBIVCZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.8
• 重原子数：
  39
• 可旋转键数：
  14
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  202
• 氢给体数：
  7
• 氢受体数：
  14

文献信息

• COMPOSITIONS AND METHODS FOR GLYCAN SEQUENCING
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20140227793A1

  公开（公告）日：2014-08-14

  Compositions and methods directed to a glycan reagent for depolymerization of a glycan having a reducing end, the glycan reagent being represented by the formula MCX, in which M is a glycan coupling group selected from oxylamines and hydrazides; C is a fixed charge group or a basic group having a proton affinity of at least 210 kcal/mol; and X is hydrogen or a free radical initiator chemically coupled to C.

  本发明涉及一种用于降解具有还原端的糖基的糖基试剂的组合物和方法，所述糖基试剂由公式MCX表示，其中M是选择自氧胺和肼的糖基偶联基；C是固定电荷基团或具有至少210 kcal/mol质子亲和力的碱性基团；X是氢或化学偶联到C的自由基引发剂。