1-[4-(3H-pyrazol-3-yl)phenyl]ethanone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-[4-(3H-pyrazol-3-yl)phenyl]ethanone
• 化学式: C₁₁H₁₀N₂O
• 分子量: 186.21
• InChiKey: KFFAGJRGSYLJJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  41.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING THE SIGNS OF PHOTOAGED SKIN
  申请人：The Procter & Gamble Company

  公开号：US20140227207A1

  公开（公告）日：2014-08-14

  Cosmetic compositions for alleviating the signs of photoaged skin containing a substituted azole. Methods for alleviating the signs of photoaged skin that include applying a cosmetic composition comprising substituted azole to a target UV-exposed skin surface. The substituted azole compound present in the cosmetic composition may be 1-phenylimidazole, 4-phenylimidazole or a combination thereof. An effective amount of the cosmetic composition is applied to the target skin surface for a period of time sufficient to alleviate at least one sign of photoaging.