(3S,4S,5Z)-2-(hydroxymethyl)-5-(hydroxymethylidene)oxolane-3,4-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3S,4S,5Z)-2-(hydroxymethyl)-5-(hydroxymethylidene)oxolane-3,4-diol
• 化学式: C₆H₁₀O₅
• 分子量: 162.14
• InChiKey: FZRJRIPXNVGOHZ-VEULTHGXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  90.2
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• METHOD FOR PRODUCING 5-HYDROXYMETHYL-2-FURFURAL OR ALKYL ETHER DERIVATIVES THEREOF USING AN ION EXCHANGE RESIN IN THE PRESENCE OF AN ORGANIC SOLVENT
  申请人：Cho Jin Ku

  公开号：US20140235881A1

  公开（公告）日：2014-08-21

  The present invention relates to a method for producing a furan-based compound using an ion exchange resin in the presence of an organic solvent. In the method for producing a furan-based compound according to the present invention, a furan-based compound is made from an aldose-type hexose compound in the presence of an organic solvent by using an anion exchange resin and a cation exchange resin. Thus, the aldose-type hexose compound obtained from biomass by simultaneously or consecutively using the anion/cation exchange resins as catalysts can be made into 5-hydroxymethyl-2-furfural (HMF) or alkyl ether derivatives thereof such as 5-alkoxymethyl-2-furfural (AMF) without using an expensive reagent. Also, since the selection of an organic solvent is not limitative and a heterogeneous catalyst can be used, separation and purification is easy and chemically stable AMF can be directly obtained. Further, the conversion efficiency of the aldose-type hexose compound is excellent, and the hexose compound can be used at a high concentration.

  本发明涉及一种在有机溶剂存在下使用离子交换树脂生产基于呋喃的化合物的方法。根据本发明的生产基于呋喃的化合物的方法，通过在有机溶剂存在下使用阴离子交换树脂和阳离子交换树脂，可以从醛糖型己糖化合物中制备基于呋喃的化合物。因此，通过同时或连续使用阴/阳离子交换树脂作为催化剂，从生物质中获得的醛糖型己糖化合物可以制成5-羟甲基-2-呋喃醛（HMF）或其烷基醚衍生物，如5-烷氧甲基-2-呋喃醛（AMF），而无需使用昂贵的试剂。此外，由于有机溶剂的选择不受限制，可以使用非均相催化剂，因此分离和纯化容易，可以直接获得化学稳定的AMF。此外，醛糖型己糖化合物的转化效率优秀，可以以高浓度使用己糖化合物。
• US9206147B2
  申请人：——

  公开号：US9206147B2

  公开（公告）日：2015-12-08