(2R,3S,5S)-2-(hydroxymethyl)-4-methoxy-5-methyloxolan-3-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,5S)-2-(hydroxymethyl)-4-methoxy-5-methyloxolan-3-ol
• 化学式: C₇H₁₄O₄
• 分子量: 162.18
• InChiKey: VNSNBCLXWIXPNN-KYDWDHDXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• NGF APTAMER AND APPLICATION THEREOF
  申请人：RIBOMIC INC.

  公开号：US20140235701A1

  公开（公告）日：2014-08-21

  The present invention provides an aptamer binding to NGF and capable of forming a potential secondary structure represented by the formula (I): wherein N is one nucleotide selected from the group consisting of A, G, C, U and T, N11-N13, N21-N23, N32-N38 and N42-N48 are the same or different and each is a bond or 1 or 2 nucleotides selected from the group consisting of A, G, C, U and T, N14, N24, N31, N41, N39 and N49 are the same or different and each is one nucleotide selected from the group consisting of A, G, C, U and T, N14 and N24, N31 and N41, and N39 and N49 each form a Watson-Crick base pair, N11-N12-N13-N14 and N21-N22-N23-N24 are nucleotide sequences capable of forming a stem structure in combination, and N31-N32-N33-N34-N35-N36-N37-N38-N39 and N41-N42-N43-N44-N45-N46-N47-N48-N49 are nucleotide sequences capable of forming a stem structure in combination.
• APTAMER AGAINST MIDKINE AND APPLICATIONS THEREOF
  申请人：RIBOMIC INC.

  公开号：US20150353933A1

  公开（公告）日：2015-12-10

  The present invention provides an aptamer binding to midkine and capable of forming a potential secondary structure represented by the formula (I): wherein X1, X2, X5 and X6 are the same or different and each is one or two nucleotides selected from the group consisting of A, G, C, U and T, or a bond, X1 and X6, and X2 and X5 each form a Watson-Crick base pairs, and X3 and X4 are the same or different and each is a nucleotide selected from A, G, C, U and T.
• US9506070B2
  申请人：——

  公开号：US9506070B2

  公开（公告）日：2016-11-29
• US9567589B2
  申请人：——

  公开号：US9567589B2

  公开（公告）日：2017-02-14