2-acetamido-2-deoxy-6-O-phosphono-alpha-D-mannopyranose | 873185-52-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-mannopyranose
• 英文别名: [(2R,3S,4R,5S,6S)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methyl dihydrogen phosphate
• CAS: 873185-52-5
• 化学式: C₈H₁₆NO₉P
• 分子量: 301.19
• InChiKey: BRGMHAYQAZFZDJ-UOLFYFMNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  166
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• METHOD FOR PRODUCING N-ACETYL-D-GLUCOSAMINE AND/OR D-GLUCOSAMINE HYDROCHLORIDE BY MICROBIAL FERMENTATION
  申请人：Sun, Lan

  公开号：EP3441473A1

  公开（公告）日：2019-02-13

  This Invention discloses a method for production of N-Acetyl-D-Glucosamine and/or D-Glucosamine Salt by microbial fermentation. The method is intended to manufacture N-Acetyl-D-Glucosamine and/or D-Glucosamine Salt in higher efficiency and higher yield, by expression of vitreoscilla hemoglobin in microorganism.

  本发明公开了一种通过微生物发酵生产N-乙酰基-D-葡萄糖胺和/或D-葡萄糖胺盐的方法。该方法旨在通过在微生物中表达玻璃体血红蛋白，以更高的效率和产量生产 N-乙酰基-D-氨基葡萄糖和/或 D-氨基葡萄糖盐。
• Microbial fermentation method for production of n-acetyl-d-glucosamine and/or d-glucosamine salt
  申请人：Sun Lan

  公开号：US11136608B2

  公开（公告）日：2021-10-05

  This Invention discloses a method for production of N-Acetyl-D-Glucosamine and/or D-Glucosamine Salt by microbial fermentation. The method is intended to manufacture N-Acetyl-D-Glucosamine and/or D-Glucosamine Salt in higher efficiency and higher yield, by expression of vitreoscilla hemoglobin in microorganism.

  本发明公开了一种通过微生物发酵生产N-乙酰基-D-葡萄糖胺和/或D-葡萄糖胺盐的方法。该方法旨在通过在微生物中表达玻璃体血红蛋白，以更高的效率和产量生产 N-乙酰基-D-氨基葡萄糖和/或 D-氨基葡萄糖盐。
• Methods of Using a Bacterial GlcNAc-6-P 2'- Epimerase to Promote Sialylation of Glycoconjugates
  申请人：Geisler Christoph

  公开号：US20130029413A1

  公开（公告）日：2013-01-31

  The present invention relates to new methods to promote sialylation of glycoconjugates, including recombinant glycoproteins, in glycoconjugate production systems. The invention relates to methods to promote efficient glycoconjugate sialylation in recombinant expression systems, by providing simpler and more economical ways to produce large intracellular pools of sialic acid precursors. The invention is directed to nucleic acids, vectors, and cells harboring vectors comprising nucleic acids encoding enzymes involved in the synthesis of sialic acid precursors, and cells harboring these nucleic acids in combination with nucleic acids encoding glycosyltransferases, including sialyltransferases, to facilitate the production of humanized recombinant glycoproteins in bacterial, fungal, plant, and animal cell expression systems. The engineered cells can be used to produce glycosylated proteins in virally-infected, transiently-transformed, or stably-transformed host cells, including lepidopteran insects and cultured cell lines derived from Spodoptera frugiperda, Trichoplusia ni , and Bombyx mori that can be infected by baculovirus expression vectors.
• US20140283154A1
  申请人：——

  公开号：US20140283154A1

  公开（公告）日：2014-09-18
• METHOD FOR PRODUCING N-ACETYL-D-GLUCOSAMINE AND/OR D-GLUCOSAMINE SALT BY MICROBIAL FERMENTATION
  申请人：Sun Lan

  公开号：US20200308615A1

  公开（公告）日：2020-10-01

  This Invention discloses a method for production of N-Acetyl-D-Glucosamine and/or D-Glucosamine Salt by microbial fermentation. The method is intended to manufacture N-Acetyl-D-Glucosamine and/or D-Glucosamine Salt in higher efficiency and higher yield, by increasing the effects of N-Acetyl-D-Mannosamine Kinase.