Methyl-(2-oxo-2-pyridin-3-ylethyl)carbamic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl-(2-oxo-2-pyridin-3-ylethyl)carbamic acid
• 英文别名: methyl-(2-oxo-2-pyridin-3-ylethyl)carbamic acid
• 化学式: C₉H₁₀N₂O₃
• 分子量: 194.19
• InChiKey: YRMYDYUJQNHDEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  70.5
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES<br/>[FR] COMPOSITIONS ET PROCÉDÉS COMPRENANT DES 2-AMINOIMIDAZOLES SUBSTITUÉS
  申请人：CURZA GLOBAL LLC

  公开号：WO2018184019A1

  公开（公告）日：2018-10-04

  The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.

  本发明提供了具有治疗活性的2-(酰胺基)咪唑，包括对癌细胞具有选择性活性的化合物，并包括这些化合物的组合物。还提供了使用和制备2-(酰胺基)咪唑的方法。
• Compositions and methods comprising substituted 2-aminoimidazoles
  申请人：Curza Global, LLC

  公开号：US11339140B2

  公开（公告）日：2022-05-24

  The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.

  本发明提出了具有治疗活性（包括对癌细胞的选择性活性）的 2-(酰氨基)咪唑以及包含它们的组合物。本发明还提出了使用和制备 2-（酰氨基）咪唑的方法。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：EP2958897A2

  公开（公告）日：2015-12-30
• COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES
  申请人：Curza Global LLC

  公开号：EP3601232A1

  公开（公告）日：2020-02-05
• [EN] COMPOUNDS USEFUL AS MODULATORS OF TRPM8<br/>[FR] COMPOSÉS UTILES COMME MODULATEURS DE TRPM8
  申请人：SENOMYX INC

  公开号：WO2014130582A2

  公开（公告）日：2014-08-28

  The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.