(2R,3S,4S,5R)-2-(hydroxymethyl)-6-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy-6-[2-(hydroxymethyl)phenoxy]oxan-2-yl]oxyoxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4S,5R)-2-(hydroxymethyl)-6-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy-6-[2-(hydroxymethyl)phenoxy]oxan-2-yl]oxyoxane-3,4,5-triol
• 化学式: C₁₈H₂₆O₁₂
• 分子量: 434.4
• InChiKey: PZPYEKYLBVTFPN-VCEXVIETSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  199
• 氢给体数：
  8
• 氢受体数：
  12

文献信息

• COMPOSITIONS AND METHODS TO INACTIVATE AND/OR REDUCE PRODUCTION OF MICROBIAL TOXINS
  申请人：BIOLOG, INC.

  公开号：EP2958429A2

  公开（公告）日：2015-12-30
• [EN] COMPOSITIONS AND METHODS TO INACTIVATE AND/OR REDUCE PRODUCTION OF MICROBIAL TOXINS<br/>[FR] COMPOSITIONS ET PROCÉDÉS D'INACTIVATION ET/OU DE RÉDUCTION DE LA PRODUCTION DE TOXINES MICROBIENNES
  申请人：BIOLOG INC

  公开号：WO2014130655A2

  公开（公告）日：2014-08-28

  The present invention is related to compositions and methods to treat, ameliorate and/or prevent morbidity and/or mortality from microbial infections. In particular, bacterial infections that are associated with the production and release of bacterial toxins. For example, many Clostridia bacteria, such as Clostridium difficile, release toxins resulting in tissue and organ damage and death, even after antibiotic therapy that either reduces or eliminates the bacteria. In particular, various peptides, polypeptides, and proteins are disclosed herein that either inactivate Clostridium difficile toxin and/or reduce Clostridium difficile toxin production.