octyl (2R,3S,5R)-5-acetamido-4-(diaminomethylideneamino)-2,3-difluoro-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: octyl (2R,3S,5R)-5-acetamido-4-(diaminomethylideneamino)-2,3-difluoro-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
• 化学式: C₂₀H₃₆F₂N₄O₇
• 分子量: 482.5
• InChiKey: VSWKZKLVAPPHTF-LMRSIIQRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  33
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  190
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• 2,3-Fluorinated Glycosides as Neuraminidase Inhibitors and Their Use as Anti-Virals
  申请人：THE UNIVERSITY OF BRITISH COLUMBIA

  公开号：US20150158899A1

  公开（公告）日：2015-06-11

  Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza.
• Neuraminidase Inhibitor Compounds, Compositions and Methods for the Use Thereof in Anti-Viral Treatments
  申请人：THE UNIVERSITY OF BRITISH COLUMBIA

  公开号：US20150216838A1

  公开（公告）日：2015-08-06

  Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza.
• US8815941B2
  申请人：——

  公开号：US8815941B2

  公开（公告）日：2014-08-26
• US8907111B2
  申请人：——

  公开号：US8907111B2

  公开（公告）日：2014-12-09
• US9221859B2
  申请人：——

  公开号：US9221859B2

  公开（公告）日：2015-12-29