3,3-Dimethyloxolan-2-one;prop-2-enoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 3,3-Dimethyloxolan-2-one;prop-2-enoic acid
• 英文别名: 3,3-dimethyloxolan-2-one;prop-2-enoic acid
• 化学式: C9H14O4
• 分子量: 186.2
• InChiKey: DZEBTTLAPLWZCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.22
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• A bitumen.
  申请人：S.A. Imperbel N.V.

  公开号：EP2821463A1

  公开（公告）日：2015-01-07

  A method for producing a bitumen, characterized in that the method comprises the mixing of a first oil pitch, comprising particles of soot and saturated oils, with a second oil pitch, comprising Heavy Pyrolysis Oil (HPO), aromatic oils and resins, said first oil originating from a distillation of waste engine lubricant and said second oil pitch being a vacuum residue of crude oil coming from a crude oil distillation process under vacuum.

  一种生产沥青的方法，其特征在于，该方法包括将由烟尘和饱和油颗粒组成的第一沥青油与由重质热解油（HPO）、芳香油和树脂组成的第二沥青油混合，所述第一沥青油源自发动机废润滑油的蒸馏，所述第二沥青油是原油蒸馏过程中在真空条件下产生的原油真空残渣。
• Injectable cell-laden biohybrid hydrogels for cardiac regeneration and related applications
  申请人：ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

  公开号：US10265439B2

  公开（公告）日：2019-04-23

  The present invention provides a temperature-responsive dual-gelling hydrogel comprising a plurality of hydrogel polymers and a polymer cross-linking moiety, wherein the LCST of the hydrogel polymers is less than 37° C., and the polymer cross-linking moiety is capable of chemically cross linking to the hydrogel polymers to form a polymer matrix.

  本发明提供了一种温度响应型双胶凝水凝胶，该水凝胶由多种水凝胶聚合物和聚合物交联分子组成，其中水凝胶聚合物的 LCST 小于 37°C，聚合物交联分子能够与水凝胶聚合物发生化学交联以形成聚合物基体。
• In situ forming hydrogel and method using same
  申请人：Arizona Board of Regents on behalf of Arizona State University

  公开号：US10780145B2

  公开（公告）日：2020-09-22

  A hydrogel (I), comprising a polymer backbone wherein an aqueous solution of the hydrogel comprises a first lower critical solution temperature, and wherein the hydrogel is configured to be converted in vivo into a modified hydrogel, and wherein an aqueous solution of the modified hydrogel comprises a second lower critical solution temperature, and wherein the second lower critical solution temperature is greater than the first lower critical solution temperature.

  一种水凝胶 (I)，包括聚合物骨架，其中水凝胶的水溶液包括第一较低临界溶液温度，并且水凝胶被配置为在体内转化为改性水凝胶，并且改性水凝胶的水溶液包括第二较低临界溶液温度，并且第二较低临界溶液温度大于第一较低临界溶液温度。
• Temperature-responsive degradable hydrogels
  申请人：Sonoran Biosciences, Inc.

  公开号：US11173210B2

  公开（公告）日：2021-11-16

  A polymer composition can include an aqueous vehicle and a temperature-responsive degradable polymer having a polymer including a LCST-imparting unit and a lactone-bearing unit including a pendent lactone group. The number of LCST-imparting units is greater than the number of lactone-bearing units. The temperature-responsive degradable polymer has an initial lower critical solution temperature (LCST) of 37° C. or below. The polymer composition can have a pH lower than 7.

  聚合物组合物可包括水性载体和温度响应型可降解聚合物，后者具有包括低溶解温度诱导单元和含内酯单元的聚合物，其中含内酯单元包括一个下垂内酯基团。LCST诱导单元的数量多于含内酯单元的数量。温度响应型可降解聚合物的初始较低临界溶液温度（LCST）为 37°C 或以下。聚合物组合物的 pH 值可低于 7。
• A METHOD TO PRODUCE A BITUMEN
  申请人：S.A. Imperbel N.V.

  公开号：EP2821463B1

  公开（公告）日：2017-09-20