Ethanol;[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;oxalic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Ethanol;[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;oxalic acid
• 英文别名: ethanol;[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;oxalic acid
• 化学式: C32H35NO9S
• 分子量: 609.7
• InChiKey: LYGOSVIJJOQIGJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.23
• 重原子数：
  43
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  193
• 氢给体数：
  5
• 氢受体数：
  11

文献信息

• [EN] OXALIC ACID ADDITION SALTS AND/OR SOLVATES OF A SELECTIVE ESTROGEN RECEPTOR MODULATOR<br/>[FR] SELS D'ADDITION D'ACIDE OXALIQUE ET/OU SOLVATES D'UN MODULATEUR SÉLECTIF DU RÉCEPTEUR D'ŒSTROGÈNES
  申请人：CIPLA HOUSE

  公开号：WO2014135834A1

  公开（公告）日：2014-09-12

  The present invention provides raloxifene oxalate, including derivatives thereof. In particular, the present invention provides solvates and/or hydrates of raloxifene oxalate, and polymorphs thereof. The present invention also provides processes for preparing the novel compounds, pharmaceutical compositions including the novel compounds and medical uses of the novel compounds.