2,2-Dihydroxydecan-4-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2-Dihydroxydecan-4-one
• 英文别名: 2,2-dihydroxydecan-4-one
• 化学式: C₁₀H₂₀O₃
• 分子量: 188.26
• InChiKey: UEYWBJHMFDLNJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Antimicrobial compositions
  申请人：Symrise AG

  公开号：US10638755B2

  公开（公告）日：2020-05-05

  Suggested is a antimicrobial agent An antimicrobial composition comprising (a) at least one acetophenone derivative of formula (I) in which R1 stands for hydrogen or methyl, and R2 stands for hydrogen, hydroxyl or a —OCH3 group, or a cosmetically or pharmaceutically acceptable salt thereof, and (b) at least one second antimicrobial agent.

  建议使用一种抗菌剂 一种抗菌剂组合物，包含 (a) 至少一种式 (I) 的苯乙酮衍生物，其中 R1 代表氢或甲基，R2 代表氢、羟基或 -OCH3 基团，或其化妆品或药剂上可接受的盐，以及 (b) 至少一种第二种抗菌剂。
• Biphase chemical peel
  申请人：L'OREAL

  公开号：US11389382B2

  公开（公告）日：2022-07-19

  A biphasic leave-on skin peel composition, being light-weight, with a pleasing feel upon application, with little to no skin irritation and discomfort. The composition includes at least one of each of alpha and beta hydroxy acids and high content of non-water miscible oil and is present from at least 20% by weight based on the total weight of the composition. The oily and water phases may be present in equal amounts (about 1:1). The composition includes water and alcohol as solvents in the water phase and may include phenylethyl resorcinol and other optional additives, may be devoid or essentially free of surfactant.

  一种双相免洗换肤组合物，重量轻，使用时感觉舒适，对皮肤几乎没有刺激和不适。该组合物包括至少一种α-羟基酸和β-羟基酸，以及高含量的不与水混溶的油脂，其含量至少占组合物总重量的 20%（按重量计）。油相和水相可以等量（约 1:1）存在。该组合物包括作为水相溶剂的水和酒精，还可包括苯乙基间苯二酚和其他可选添加剂，可以不含或基本不含表面活性剂。
• SILICONE-FREE, LOW-FRICTION CLEANSER WITH HIGH-FOAMING PROPERTIES
  申请人：L'OREAL

  公开号：EP4021393A1

  公开（公告）日：2022-07-06
• Antimicrobial Compositions
  申请人：SYMRISE AG

  公开号：US20160015031A1

  公开（公告）日：2016-01-21

  Suggested is a antimicrobial agent An antimicrobial composition comprising (a) at least one acetophenone derivative of formula (I) in which R 1 stands for hydrogen or methyl, and R 2 stands for hydrogen, hydroxyl or a —OCH 3 group, or a cosmetically or pharmaceutically acceptable salt thereof, and (b) at least one second antimicrobial agent.
• BIPHASE CHEMICAL PEEL
  申请人：L'OREAL

  公开号：US20210093530A1

  公开（公告）日：2021-04-01

  A biphasic leave-on skin peel composition, being light-weight, with a pleasing feel upon application, with little to no skin irritation and discomfort. The composition includes at least one of each of alpha and beta hydroxy acids and high content of non-water miscible oil and is present from at least 20% by weight based on the total weight of the composition. The oily and water phases may be present in equal amounts (about 1:1). The composition includes water and alcohol as solvents in the water phase and may include phenylethyl resorcinol and other optional additives, may be devoid or essentially free of surfactant.