(13S,15S)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-18-ol

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 石蒜科生物碱
• 英文名称: (13S,15S)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-18-ol
• 化学式: C₁₇H₁₉NO₄
• 分子量: 301.34
• InChiKey: YGPRSGKVLATIHT-XYWUZFKPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  51.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Composition of extracts from the genus Hippeastrum and the use of their components for the production of pharmaceuticals and dietary supplements
  申请人：BERBEE BEHEER BV.

  公开号：US20170182111A1

  公开（公告）日：2017-06-29

  A composition of extracts from the genus Hippeastrum and their components is intended for the production of pharmaceuticals and dietary supplements. The composition consists of galanthamine from 40% to 98%, haemanthamine from 0.01% to 35%, narwedine from 0.01% to 10%, and/or other alkaloids of homolycorine-, and/or tazettine-, and/or monthanine- and/or haemanthamine- and/or galanthamine- and/or lycorine-type from 0.001% to 35%, and non-alkaloid plant metabolites from 0.001 to 1%, derived from the total extract of the genus Hippeastrum . The alkaloid content can vary from 0.01% to 99% and non-alkaloid plant metabolites and/or other inactive excipients and/or solvents from 1% to 99.9%, respectively. The composition may be in dry or liquid form. It is used to isolate pure compounds of haemanthamine and galanthamine.
• [EN] EXTRACT OF HIPPEASTRUM PAPILIO RICH IN GALANTHAMINE<br/>[FR] EXTRAIT DE HIPPEASTRUM PAPILIO RICHE EN GALANTHAMINE
  申请人：BERBEE BEHEER BV

  公开号：WO2014134692A1

  公开（公告）日：2014-09-12

  The composition of extracts from the genus Hippeastrum and their components is intended for the production of pharmaceuticals and dietary supplements. The composition consists of galanthamine from 40% to 98%, haemanthamine from 0.01 % to 35%, narwedine from 0.01 % to 10%, and/or other alkaloids of homolycorine-, and/or tazettine-, and/or monthanine- and/or haemanthamine- and/or galanthamine- and/or lycorine-type from 0.001 % to 35%, and non-alkaloid plant metabolites from 0.001 to 1%, derived from the total extract of the genus Hippeastrum. The alkaloid content can vary from 0.01 % to 99% and non-alkaloid plant metabolites and/or other inactive excipients and/or solvents from 1% to 99,9%, respectively. The composition may be in dry or liquid form. It is used to isolate pure compounds of haemanthamine and galanthamine.