The invention relates to pharmaceutical compositions comprising 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8-yl)-1-(4-fluorophenyl)butan-1-one in toluenesulfonic acid addition salt form:
and methods of use in the treatment of diseases involving the 5-HT2A receptor pathway, the serotonin transporter (SERT) pathway and/or the dopamine D2 receptor pathway signaling systems.
本发明涉及包含甲
苯磺酸加成盐形式的 4-((6bR,10aS)-3-甲基-2,3,6b,9,10,10a-六氢-1H,7H-
吡啶并[3′,4′:4,5]
吡咯并[1,2,3-de]
喹喔啉-8-基)-1-(4-
氟苯基)丁-1-酮的药物组合物:
以及用于治疗涉及 5-HT2A 受体通路、5-羟
色胺转运体 (
SERT) 通路和/或
多巴胺 D2 受体通路信号系统的疾病的方法。