2-[[2-Acetyl-5-(2-propan-2-ylpyrazol-3-yl)-1,2,3,6-tetrahydropyridin-4-yl]methoxy]-6-hydroxybenzaldehyde

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[[2-Acetyl-5-(2-propan-2-ylpyrazol-3-yl)-1,2,3,6-tetrahydropyridin-4-yl]methoxy]-6-hydroxybenzaldehyde
• 英文别名: 2-[[2-acetyl-5-(2-propan-2-ylpyrazol-3-yl)-1,2,3,6-tetrahydropyridin-4-yl]methoxy]-6-hydroxybenzaldehyde
• 化学式: C₂₁H₂₅N₃O₄
• 分子量: 383.4
• InChiKey: VOTZXNQNUWANTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  93.4
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN
  申请人：Global Blood Therapeutics, Inc.

  公开号：EP2970315A1

  公开（公告）日：2016-01-20
• [EN] COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN<br/>[FR] COMPOSÉS ET LEURS UTILISATIONS POUR LA MODULATION DE L'HÉMOGLOBINE
  申请人：GLOBAL BLOOD THERAPEUTICS INC

  公开号：WO2014150289A1

  公开（公告）日：2014-09-25

  Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.