2,3,4,5,6-pentafluoro-N-[3'-hydroxy-3-oxo-6'-[(3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyspiro[2-benzofuran-1,9'-xanthene]-5-yl]benzamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,4,5,6-pentafluoro-N-[3'-hydroxy-3-oxo-6'-[(3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyspiro[2-benzofuran-1,9'-xanthene]-5-yl]benzamide
• 化学式: C₃₃H₂₂F₅NO₁₁
• 分子量: 703.5
• InChiKey: GVXDGNQYWBPPGC-FZLFGTEBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  50
• 可旋转键数：
  5
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  184
• 氢给体数：
  6
• 氢受体数：
  16

文献信息

• STERILIZATION INDICATOR INCLUDING A SIMPLIFIED GENETICALLY ENGINEERED BIOLOGICAL INDICATOR
  申请人：American Sterilizer Company

  公开号：EP2970992A1

  公开（公告）日：2016-01-20
• [EN] STERILIZATION INDICATOR INCLUDING A SIMPLIFIED GENETICALLY ENGINEERED BIOLOGICAL INDICATOR<br/>[FR] INDICATEUR DE STÉRILISATION INCLUANT UN INDICATEUR BIOLOGIQUE SIMPLIFIÉ GÉNÉTIQUEMENT MODIFIÉ
  申请人：AMERICAN STERILIZER CO

  公开号：WO2014149379A1

  公开（公告）日：2014-09-25

  A sterilization indicator, including a first compartment containing a genetically engineered biological indicator, and a second compartment containing an enzyme substrate, the second compartment adapted to maintain the enzyme substrate separate from the biological indicator during sterilization, and to permit the enzyme substrate to contact the biological indicator after the biological indicator has been exposed to the sterilization medium; in which the genetically engineered biological indicator comprises at least one test organism and at least one reporter gene suitable for producing an indicator enzyme, the reporter gene being taken up by the test organism; and the test organism is free of any active or activatable repressor gene that would inhibit expression of the reporter gene if present in the test organism or sterilization indicator, and the indicator enzyme and the enzyme substrate are selected such that enzymatic action of the indicator enzyme upon the enzyme substrate yields a detectable signal.