(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxane-2-carbothialdehyde

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxane-2-carbothialdehyde
• 化学式: C₇H₁₂O₅S
• 分子量: 208.23
• InChiKey: RAZJTJNGLFDKPL-PZRMXXKTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  111
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• THIOSACCHARIDE MUCOLYTIC AGENTS
  申请人：The Regents of the University of California

  公开号：EP2968215A2

  公开（公告）日：2016-01-20
• [EN] THIOSACCHARIDE MUCOLYTIC AGENTS<br/>[FR] AGENTS MUCOLYTIQUES THIOSACCHARIDIQUES
  申请人：UNIV CALIFORNIA CORP

  公开号：WO2014153009A2

  公开（公告）日：2014-09-25

  There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
• [EN] AIRWAY MUCUS IMPACTION<br/>[FR] IMPACTION DE MUCUS DES VOIES RESPIRATOIRES
  申请人：UNIV CALIFORNIA

  公开号：WO2017197360A1

  公开（公告）日：2017-11-16

  Provided herein are, inter alia, methods and systems for detecting mucus in the lungs of a subject. Aspects provide methods and systems for the diagnosis, prognosis, characterization, detection, and treatment of asthma, chronic obstructive pulmonary disease, and type 2 inflammation.