(1-Oxo-1-phenylhex-5-yn-2-yl)carbamic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1-Oxo-1-phenylhex-5-yn-2-yl)carbamic acid
• 英文别名: (1-oxo-1-phenylhex-5-yn-2-yl)carbamic acid
• 化学式: C₁₃H₁₃NO₃
• 分子量: 231.25
• InChiKey: XDAVHOQCCJCHOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES
  申请人：Codexis, Inc.

  公开号：EP2780448B1

  公开（公告）日：2019-09-11
• IMMOBILIZED KETOREDUCTASES AND PROCESS FOR MAKING AND USING IMMOBILIZED KETOREDUCTASE
  申请人：Merck Sharp & Dohme Corp.

  公开号：EP2970927A1

  公开（公告）日：2016-01-20
• [EN] IMMOBILIZED KETOREDUCTASES AND PROCESS FOR MAKING AND USING IMMOBILIZED KETOREDUCTASE<br/>[FR] CÉTORÉDUCTASES IMMOBILISÉES ET PROCÉDÉ DE FABRICATION ET D'UTILISATION DE CÉTORÉDUCTASE IMMOBILISÉE
  申请人：MERCK SHARP & DOHME

  公开号：WO2014150633A1

  公开（公告）日：2014-09-25

  The invention is directed to immobilized ketoreductases and methods of making and using them. Enzymes are protein molecules which serve to accelerate the chemical reactions of living cells (often by several orders of magnitude). Without enzymes, most biochemical reactions would be too slow to even carry out life processes. Enzymes display great specificity and are not permanently modified by their participation in reactions. Since they are not changed during the reactions, enzymes can be cost effectively used as catalysts for a desired chemical transformation.