Einecs 272-223-3 | 68784-15-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Einecs 272-223-3
• 英文别名: azane;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
• CAS: 68784-15-6
• 化学式: C6H15NO6
• 分子量: 197.19
• InChiKey: QFWSIJKSJPEHCF-BTVCFUMJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.22
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  119
• 氢给体数：
  6
• 氢受体数：
  7

文献信息

• [EN] COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR LA THÉRAPIE CELLULAIRE ADOPTIVE
  申请人：MEMORIAL SLOAN KETTERING CANCER CENTER

  公开号：WO2019006467A1

  公开（公告）日：2019-01-03

  Provided herein are compositions and methods for adoptive cell therapy comprising engineered immune cells that express an antigen-targeted chimeric antigen receptor and a prodrug converting enzyme for the treatment of inflammation, inflammatory diseases, or pathogenic infections.

  本文提供了一种采用工程免疫细胞的细胞治疗组合物和方法，这些免疫细胞表达靶向抗原的嵌合抗原受体和一种前药转化酶，用于治疗炎症、炎症性疾病或病原体感染。
• Kyberdrug as autovaccines with immune-regulating effects
  申请人：——

  公开号：US20020155997A1

  公开（公告）日：2002-10-24

  The present invention is directed to a “Kyberdrug” and to a pharmaceutical composition containing an effective amount of the Kyberdrug and a pharmaceutical carrier therefor, and its medicinal use as an immune modulating drug exhibiting autovaccine-like activities.

  本发明涉及一种“Kyberdrug”，以及含有Kyberdrug有效量和药用载体的制药组合物，以及其作为一种免疫调节药物展示自身疫苗样活性的药用。
• BIOPSY METHODS AND DEVICES
  申请人：INDICATOR SYSTEMS INTERNATIONAL, INC.

  公开号：US20180328933A1

  公开（公告）日：2018-11-15

  Disclosed are methods for detecting remnant cancer cells in a tissue sample.

  本发明涉及一种检测组织样本中残留癌细胞的方法。
• COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF
  申请人：Ding Ke

  公开号：US20110071148A1

  公开（公告）日：2011-03-24

  The compounds according to formula VIII, their pharmaceutically acceptable acid or base addition salts, and the uses thereof is disclosed. These compounds and their pharmaceutically acceptable acid or base addition salts can be used for the preparing a medicament for modulating estrogen related receptor (ERR), and treating metabolic diseases, such as high blood fat, fatty liver, hyperglycemia, diabetes, obesity, etc. The definition of the groups of the formula is defined as the description.

  本文公开了按照式VIII公式的化合物，其药学上可接受的酸或碱盐，以及它们的用途。这些化合物及其药学上可接受的酸或碱盐可用于制备用于调节雌激素相关受体（ERR）和治疗代谢性疾病（如高血脂、脂肪肝、高血糖、糖尿病、肥胖症等）的药物。式中各基团的定义如描述中所定义。
• Amino, Amino Acid or Peptide Conjugates of Retinoic Acid
  申请人：Beumer Raphael

  公开号：US20070270472A1

  公开（公告）日：2007-11-22

  The invention provides the use of retinoyl derivatives for the cosmetic treatment or prophylaxis of wrinkles, skin aging and/or for thickening the epidermis.

  本发明提供了利用维甲酸酯类化合物进行美容治疗或预防皱纹、皮肤老化和/或增厚表皮的方法。