4-[(5-Bromo-2-thienyl)carbonyl]benzoic acid | 887405-29-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-[(5-Bromo-2-thienyl)carbonyl]benzoic acid
• 英文别名: 4-(5-bromothiophene-2-carbonyl)benzoic acid
• CAS: 887405-29-0
• 化学式: C₁₂H₇BrO₃S
• 分子量: 311.15
• InChiKey: HEWSOSHUXICSRM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  82.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS
  申请人：Rutgers, The State University of New Jersey

  公开号：US20220202772A1

  公开（公告）日：2022-06-30

  The disclosure provides in one aspect a method of treating, ameliorating, and/or preventing toxicity caused by a ribosome inactivating protein (RIP) in a subject. In certain embodiments, the method comprises administering to the subject a therapeutically effective amount of at least one compound of the disclosure.